How to study biofilms: technological advancements in clinical biofilm research.
How to study biofilms: technological advancements in clinical biofilm research.
复制标题
DOI：
10.3389/fcimb.2023.1335389
复制
发表时间：
2023
影响因子：
5.7
通讯作者：
中科院分区：
文献类型：
--
作者：
生物膜形成是细菌和真菌常用的重要生存策略，它们包埋在有机聚合物的保护性细胞外基质中。它们在自然界中无处不在，包括人类和其他动物，它们可以是表面和非表面相关的，使它们能够在身体的许多不同部位生长。生物膜也很复杂，形成多微生物群落，由于其独特的生长动力学而难以根除，与生物膜相关的临床感染是医疗保健环境中的巨大负担，因为它们通常难以诊断和治疗。我们对生物膜形成和发展的理解是一个快节奏的重要研究焦点。本文综述了近年来临床生物膜的研究进展，包括生物膜的体外和体内模型、成像技术和生物膜功能分析技术。
Biofilm formation is an important survival strategy commonly used by bacteria and fungi, which are embedded in a protective extracellular matrix of organic polymers. They are ubiquitous in nature, including humans and other animals, and they can be surface- and non-surface-associated, making them capable of growing in and on many different parts of the body. Biofilms are also complex, forming polymicrobial communities that are difficult to eradicate due to their unique growth dynamics, and clinical infections associated with biofilms are a huge burden in the healthcare setting, as they are often difficult to diagnose and to treat. Our understanding of biofilm formation and development is a fast-paced and important research focus. This review aims to describe the advancements in clinical biofilm research, including both in vitro and in vivo biofilm models, imaging techniques and techniques to analyse the biological functions of the biofilm.
登录
查看更多内容
影响因子：
4.6
作者：
通讯作者：
--
影响因子：
4.5
作者：
Robertsson C;Svensäter G;Blum Z;Jakobsson ME;Wickström C
通讯作者：
Wickström C
影响因子：
6.8
作者：
通讯作者：
--
影响因子：
--
作者：
Germano F;Bramanti E;Arcuri C;Cecchetti F;Cicciù M
通讯作者：
Cicciù M
DOI：
10.3390/diagnostics11101746
发表时间：
2021-09-23
期刊：
Diagnostics (Basel, Switzerland)
影响因子：
--
作者：
Pouget C;Dunyach-Remy C;Pantel A;Schuldiner S;Sotto A;Lavigne JP
通讯作者：
Lavigne JP