From ventral-medial to dorsal-lateral striatum: neural correlates of reward-guided decision-making.
From ventral-medial to dorsal-lateral striatum: neural correlates of reward-guided decision-making.
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DOI：
10.1016/j.nlm.2014.05.003
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发表时间：
2015-01
影响因子：
2.7
通讯作者：
Roesch MR
中科院分区：
文献类型：
--
作者：
Burton AC;Nakamura K;Roesch MR
纹状体对于奖励引导和习惯性行为至关重要。解剖学和干扰研究表明纹状体内存在功能异质性。内侧区域，如伏隔核和背内侧纹状体在目标导向行为中发挥作用，而背外侧纹状体对于控制习惯性行为至关重要。纹状体的细分在地形上与不同的皮质和皮质下结构相连，形成携带与边缘、联想和感觉运动功能相关信息的通道。在这里，我们描述的数据表明，随着一个人从腹内侧纹状体发展到背外侧纹状体，存在从更突出的价值编码到与决策的联想和运动方面更密切相关的活动的转变。此外，我们将描述数据表明纹状体回路与控制行为并行工作，并且当功能被破坏时纹状体内的区域可以相互补偿。
The striatum is critical for reward-guided and habitual behavior. Anatomical and interference studies suggest a functional heterogeneity within striatum. Medial regions, such as nucleus accumbens core and dorsal medial striatum play roles in goal-directed behavior, while dorsal lateral striatum is critical for control of habitual action. Subdivisions of striatum are topographically connected with different cortical and subcortical structures forming channels that carry information related to limbic, associative, and sensorimotor functions. Here, we describe data showing that as one progresses from ventral-medial to dorsal-lateral striatum, there is a shift from more prominent value encoding to activity more closely related to associative and motor aspects of decision-making. In addition, we will describe data suggesting that striatal circuits work in parallel to control behavior and that regions within striatum can compensate for each other when functions are disrupted.
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影响因子：
5.3
作者：
Nakamura, Kae;Santos, Gustavo S.;Nakahara, Hiroyuki
通讯作者：
Nakahara, Hiroyuki
影响因子：
3.3
作者：
Lichtenberg NT;Kashtelyan V;Burton AC;Bissonette GB;Roesch MR
通讯作者：
Roesch MR
影响因子：
3.7
作者：
Bissonette GB;Burton AC;Gentry RN;Goldstein BL;Hearn TN;Barnett BR;Kashtelyan V;Roesch MR
通讯作者：
Roesch MR
影响因子：
16.2
作者：
Bromberg-Martin, Ethan S.;Matsumoto, Masayuki;Hikosaka, Okihide
通讯作者：
Hikosaka, Okihide
影响因子：
16.6
作者：
Gremel, Christina M.;Costa, Rui M.
通讯作者：
Costa, Rui M.