Effects of air pollution on adverse birth outcomes and pregnancy complications in the U.S. state of Kansas (2000-2015).
Effects of air pollution on adverse birth outcomes and pregnancy complications in the U.S. state of Kansas (2000-2015).
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DOI：
10.1038/s41598-023-48329-5
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发表时间：
2023-12-06
影响因子：
4.6
通讯作者：
中科院分区：
文献类型：
--
作者：
新生儿死亡率和发病率往往是由早产和出生体重不足造成的。妊娠期糖尿病（GDM）和妊娠期高血压（GH）是妊娠期最常见的并发症。然而，关于空气污染对不良分娩结果和妊娠并发症影响的证据好坏参半。研究纳入了2000年1月1日至2015年12月31日期间在堪萨斯怀孕至少27周的单胎活产婴儿。使用时空集合模型估计了三个月特定的和总的妊娠暴露于二氧化氮（NO2），空气动力学直径小于2.5 μm的颗粒物（PM2.5）和臭氧（O3），并分配给产妇居住人口普查区。应用逻辑回归、离散时间生存和线性模型评估相关性。在调整人口统计学和社会经济地位（SES）因素后，我们发现第二和第三个三个月的增加和总的妊娠O3暴露与早产显着相关。暴露于中期和晚期妊娠O3显着与出生体重较低，暴露于NO2在前三个月与GDM的风险增加。O3暴露在前三个月与GH的风险升高有关。我们没有观察到不良妊娠和出生结果与PM2.5暴露之间的一致性关联。我们的研究结果表明，妊娠期间O3暴露增加与早产、GH和出生体重下降的风险增加之间存在正相关。我们的工作支持限制人口暴露于空气污染，这可能会降低不良出生和怀孕结果的可能性。
Neonatal mortality and morbidity are often caused by preterm birth and lower birth weight. Gestational diabetes mellitus (GDM) and gestational hypertension (GH) are the most prevalent maternal medical complications during pregnancy. However, evidence on effects of air pollution on adverse birth outcomes and pregnancy complications is mixed. Singleton live births conceived between January 1st, 2000, and December 31st, 2015, and reached at least 27 weeks of pregnancy in Kansas were included in the study. Trimester-specific and total pregnancy exposures to nitrogen dioxide (NO2), particulate matter with an aerodynamic diameter less than 2.5 μm (PM2.5), and ozone (O3) were estimated using spatiotemporal ensemble models and assigned to maternal residential census tracts. Logistic regression, discrete-time survival, and linear models were applied to assess the associations. After adjustment for demographics and socio-economic status (SES) factors, we found increases in the second and third trimesters and total pregnancy O3 exposures were significantly linked to preterm birth. Exposure to the second and third trimesters O3 was significantly associated with lower birth weight, and exposure to NO2 during the first trimester was linked to an increased risk of GDM. O3 exposures in the first trimester were connected to an elevated risk of GH. We didn’t observe consistent associations between adverse pregnancy and birth outcomes with PM2.5 exposure. Our findings indicate there is a positive link between increased O3 exposure during pregnancy and a higher risk of preterm birth, GH, and decreased birth weight. Our work supports limiting population exposure to air pollution, which may lower the likelihood of adverse birth and pregnancy outcomes.
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DOI：
10.1097/ede.0b013e31824523f0
发表时间：
2012-03
期刊：
Epidemiology (Cambridge, Mass.)
影响因子：
--
作者：
Bind MA;Baccarelli A;Zanobetti A;Tarantini L;Suh H;Vokonas P;Schwartz J
通讯作者：
Schwartz J
妊娠糖尿病（GDM）和妊娠高血压（GH）对胎盘形态变化的影响。
DOI：
10.47162/rjme.61.2.07
发表时间：
2020-04
期刊：
Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie
影响因子：
--
作者：
Istrate-Ofiţeru AM;Berceanu C;Berceanu S;Busuioc CJ;Roşu GC;Diţescu D;Grosu F;Voicu NL
通讯作者：
Voicu NL
影响因子：
3.7
作者：
DeFranco E;Hall E;Hossain M;Chen A;Haynes EN;Jones D;Ren S;Lu L;Muglia L
通讯作者：
Muglia L
影响因子：
3.6
作者：
Getaneh T;Negesse A;Dessie G;Desta M
通讯作者：
Desta M
影响因子：
2.9
作者：
Beam, Andrew L.;Fried, Inbar;Armstrong, Joanne
通讯作者：
Armstrong, Joanne