Neonatal abstinence syndrome: Neurobehavior at 6 weeks of age in infants with or without pharmacological treatment for withdrawal.
Neonatal abstinence syndrome: Neurobehavior at 6 weeks of age in infants with or without pharmacological treatment for withdrawal.
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DOI:
10.1002/dev.21532
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发表时间:
2017-07
影响因子:
2.2
通讯作者:
Hayes MJ
中科院分区:
文献类型:
--
作者:
Heller NA;Logan BA;Morrison DG;Paul JA;Brown MS;Hayes MJ
Use and abuse of prescription opioids and concomitant increase in Neonatal Abstinence Syndrome (NAS), a condition that may lead to protracted pharmacological treatment in more than 60% of infants, has tripled since 2000. This study assessed neurobehavioral development using the NICU Network Neurobehavioral Scale in six-week old infants with prenatal methadone exposure who did (NAS+; n=23) or did not (NAS−; n=16) require pharmacological treatment for NAS severity determined by Finnegan Scale. An unexposed, demographically similar group of infants matched for age served as comparison (COMP; n=21). NAS+, but not NAS− group, had significantly lower scores on the regulation (p<.01) and quality of movement (p<.01) summary scales than the COMP group. The NAS+ and NAS− groups had higher scores on the stress-abstinence scale than the COMP group (p<.05). NAS diagnosis (NAS+) was associated with poorer regulation and quality of movement at six weeks of age compared to infants without prenatal methadone exposure from the same demographic.
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DOI:
10.1111/j.1360-0443.2012.04040.x
发表时间:
2012-11
期刊:
Addiction (Abingdon, England)
影响因子:
--
作者:
Coyle MG;Salisbury AL;Lester BM;Jones HE;Lin H;Graf-Rohrmeister K;Fischer G
通讯作者:
Fischer G
影响因子:
2.3
作者:
Bart G
通讯作者:
Bart G
影响因子:
2
作者:
Jones, Hendree E.;O'Grady, Kevin E.;Jansson, Lauren M.
通讯作者:
Jansson, Lauren M.
影响因子:
2.9
作者:
Brown, M. S.;Hayes, M. J.;Thornton, L. M.
通讯作者:
Thornton, L. M.
影响因子:
6
作者:
Burns, Lucy;Mattick, Richard P.;Wallace, Cate
通讯作者:
Wallace, Cate