The cutoff values of visceral fat area and waist circumference for identifying subjects at risk for metabolic syndrome in elderly Korean: Ansan Geriatric (AGE) cohort study.
The cutoff values of visceral fat area and waist circumference for identifying subjects at risk for metabolic syndrome in elderly Korean: Ansan Geriatric (AGE) cohort study.
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DOI：
10.1186/1471-2458-9-443
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发表时间：
2009-12-02
影响因子：
4.5
通讯作者：
Kim NH
中科院分区：
文献类型：
--
作者：
Seo JA;Kim BG;Cho H;Kim HS;Park J;Baik SH;Choi DS;Park MH;Jo SA;Koh YH;Han C;Kim NH
在韩国，根据主要针对中年人的分析，建议诊断代谢综合征（MetS）的腰围（WC）临界值为男性90厘米，女性85厘米。由于衰老与脂肪增加有关，尤其是腹部内脏脂肪，因此WC的临界值可能会根据年龄而有所不同。此外，内脏腹部脂肪面积（VFA）对于预测老年人 MetS 的有用性尚未研究。我们的目的是提出 WC 和 VFA 标准，并比较 WC 和 VFA 的可预测性，以识别有 MetS 风险的人群。这项横断面研究从一项正在进行的、前瞻性的、以人群为基础的研究——安山老年人 (AGE) 队列研究中选择了总共 689 名年龄 ≥ 63 岁的老年受试者（308 名男性，381 名女性）。 VFA 通过单层腹部计算机断层扫描测量。除 WC（血糖、血压、血清甘油三酯和 HDL 胆固醇水平）外，代谢危险因素均使用修改后的 NCEP-ATP III 标准定义。我们通过接受者操作特征 (ROC) 曲线分析估计了 VFA 和 WC 识别至少其中两个因素的准确性。 308 名男性中的 203 名和 381 名女性中的 280 名有 ≥ 2 种代谢危险因素。 VFA 预测是否存在 ≥ 2 种代谢危险因素的 ROC 曲线下面积 (AUC) 值与 WC 没有显着差异（男性为 0.735 和 0.750；女性为 0.715 和 0.682；VFA 和 WC 的 AUC 值分别）。预测是否存在 ≥ 2 个代谢危险因素的 VFA 和 WC 最佳临界点分别为：男性 92.6 cm2 和 86.5 cm，女性 88.9 cm2 和 86.5 cm。 WC 在识别有 MetS 风险的老年人方面与 VFA 具有相当的能力。韩国老年男性和女性在评估 MetS 风险时，VFA 和 WC 测量值的截止点非常相似。可以考虑 WC 的年龄特定截止点来识别有 MetS 风险的受试者。
In Korea, the cutoff values of waist circumference (WC) for the identification of metabolic syndrome (MetS) were suggested to be 90 cm for men and 85 cm for women based on the analysis mainly in middle-aged adults. As aging is associated with increased fat, especially abdominal visceral fat, the cutoff value of WC may differ according to age. In addition, the usefulness of visceral abdominal fat area (VFA) to predict MetS in the elderly has not been studied yet. We aimed to suggest WC and VFA criteria and to compare the predictability of WC and VFA to identify people at risk for MetS. A total of 689 elderly subjects aged ≥63 years (308 men, 381 women) were chosen in this cross-sectional study from an ongoing, prospective, population-based study, the Ansan Geriatric (AGE) cohort study. VFA was measured by single slice abdominal computed tomography scanning. The metabolic risk factors except WC (plasma glucose, blood pressure, serum triglycerides and HDL cholesterol levels) were defined using modified NCEP-ATP III criteria. We estimated the accuracy of VFA and WC for identifying at least two of these factors by receiver operating characteristic (ROC) curve analysis. Two hundred three of 308 men and 280 of 381 women had ≥2 metabolic risk factors. The area under the ROC curve (AUC) value for VFA to predict the presence of ≥2 metabolic risk factors was not significantly different from that for WC (men, 0.735 and 0.750; women, 0.715 and 0.682; AUC values for VFA and WC, respectively). The optimal cutoff points for VFA and WC for predicting the presence of ≥2 metabolic risk factors were 92.6 cm2 and 86.5 cm for men and 88.9 cm2 and 86.5 cm for women. WC had comparable power with VFA to identify elderly people who are at risk for MetS. Elderly Korean men and women had very similar cutoff points for both VFA and WC measurements for estimating the risk of MetS. Age-specific cutoff point for WC might be considered to identify subjects at risk for MetS.
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影响因子：
120.7
作者：
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通讯作者：
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影响因子：
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作者：
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