Volitional regulation of emotions produces distributed alterations in connectivity between visual, attention control, and default networks.
Volitional regulation of emotions produces distributed alterations in connectivity between visual, attention control, and default networks.
复制标题
DOI：
10.1016/j.neuroimage.2013.11.006
复制
发表时间：
2014-04-01
期刊：
影响因子：
5.7
通讯作者：
Swain JE
中科院分区：
文献类型：
--
作者：
Sripada C;Angstadt M;Kessler D;Phan KL;Liberzon I;Evans GW;Welsh RC;Kim P;Swain JE
意志调节情绪的能力对健康和幸福至关重要。虽然情绪调节过程中的神经激活模式已经得到了很好的表征，但区域之间的连接模式仍然很少探索。越来越多的人认识到，人类大脑被组织成大规模的内在连接网络（ICN），其相互关系在心理任务期间以特有的方式发生变化。在这项针对54名健康个体的fMRI研究中，我们研究了由情绪调节策略重新评价产生的ICN内部和之间的连接变化。为了全面了解连接变化，我们利用了连接组心理生理相互作用（PPI），这是标准单种子PPI方法的全脑推广。特别是，我们在整个皮层放置的837个ROI上成对量化了PPI连接。我们发现，与维持一个人的情绪反应相比，参与重新评价产生了强大的和分布式的功能连接，包括视觉，背侧注意，额顶叶和默认网络的变化。特别是视觉网络增加了与多个ICN的连接，包括背侧注意和默认网络。我们解释这些发现的作用，这些网络在调解关键组成过程中的情绪调节，包括视觉处理，刺激的显着性，注意力控制，解释和语境化的刺激。我们的研究结果为我们理解情绪调节的神经基础增加了一个新的网络视角，并强调了连接组学方法在全面研究跨任务条件的连接调制方面可以发挥有价值的作用。
The ability to volitionally regulate emotions is critical to health and well-being. While patterns of neural activation during emotion regulation have been well characterized, patterns of connectivity between regions remain less explored. It is increasingly recognized that the human brain is organized into large-scale intrinsic connectivity networks (ICNs) whose interrelationships are altered in characteristic ways during psychological tasks. In this fMRI study of 54 healthy individuals, we investigated alterations in connectivity within and between ICNs produced by the emotion regulation strategy of reappraisal. In order to gain a comprehensive picture of connectivity changes, we utilized connectomic psychophysiological interactions (PPI), a whole-brain generalization of standard single-seed PPI methods. In particular, we quantified PPI connectivity pair-wise across 837 ROIs placed throughout the cortex. We found that compared to maintaining one’s emotional responses, engaging in reappraisal produced robust and distributed alterations in functional connections involving visual, dorsal attention, frontoparietal, and default networks. Visual network in particular increased connectivity with multiple ICNs including dorsal attention and default networks. We interpret these findings in terms of the role of these networks in mediating critical constituent processes in emotion regulation, including visual processing, stimulus salience, attention control, and interpretation and contextualization of stimuli. Our results add a new network perspective to our understanding of the neural underpinnings of emotion regulation, and highlight that connectomic methods can play a valuable role in comprehensively investigating modulation of connectivity across task conditions.
登录
查看更多内容
影响因子：
5.7
作者：
Barrett LF;Satpute AB
通讯作者：
Satpute AB
DOI：
10.1073/pnas.0504136102
发表时间：
2005-07-05
影响因子：
11.1
作者：
Fox, MD;Snyder, AZ;Raichle, ME
通讯作者：
Raichle, ME
DOI：
10.1111/j.2517-6161.1995.tb02031.x
发表时间：
1995-01-01
影响因子：
5.8
作者：
BENJAMINI, Y;HOCHBERG, Y
通讯作者：
HOCHBERG, Y
影响因子：
4.8
作者：
Gao, Wei;Lin, Weili
通讯作者：
Lin, Weili
影响因子：
5.7
作者：
Diekhof, Esther Kristina;Geier, Katharina;Gruber, Oliver
通讯作者：
Gruber, Oliver