The mosquito holobiont: fresh insight into mosquito-microbiota interactions.
The mosquito holobiont: fresh insight into mosquito-microbiota interactions.
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DOI：
10.1186/s40168-018-0435-2
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发表时间：
2018-03-20
期刊：
影响因子：
15.5
通讯作者：
Valiente Moro C
中科院分区：
文献类型：
--
作者：
Guégan M;Zouache K;Démichel C;Minard G;Tran Van V;Potier P;Mavingui P;Valiente Moro C
全息生物的概念最初是为珊瑚生态系统开发的，但已经扩展到多种生物，包括植物和其他动物。昆虫相关微生物群落的研究已经提供了强有力的证据，表明共生细菌在宿主生物学中起着重要作用。然而，对这些共生关系的理解主要局限于食植物昆虫，而宿主相关微生物群在食血昆虫媒介中的作用仍未被探索。蚊子是一个主要的全球公共卫生问题，与此同时，面临感染风险的人数也在增加。蚊媒疾病在全球范围内的出现和再次出现导致许多研究人员对蚊子宿主及其相关微生物群进行研究。尽管这些研究大多是描述性的，但它们已经对蚊子种群所承载的细菌群落进行了广泛的描述。本文综述了蚊子微生物群研究领域的主要进展和进展，同时也介绍了其他微生物及其组成和多样性的环境因素。讨论包括微生物群功能作用的最新发现，并强调它们与宿主生物学和病原体传播的相互作用。深入了解多方相互作用的生态学，我们认为赋予蚊子及其微生物群“全息生物”一词有助于全面了解媒介的病理系统功能，从而能够制定创新和有效的新型媒介控制策略。本文的在线版本（10.1186/s40168-018-0435-2）包含补充材料，可供授权用户使用。
The holobiont concept was first developed for coral ecosystems but has been extended to multiple organisms, including plants and other animals. Studies on insect-associated microbial communities have produced strong evidence that symbiotic bacteria play a major role in host biology. However, the understanding of these symbiotic relationships has mainly been limited to phytophagous insects, while the role of host-associated microbiota in haematophagous insect vectors remains largely unexplored. Mosquitoes are a major global public health concern, with a concomitant increase in people at risk of infection. The global emergence and re-emergence of mosquito-borne diseases has led many researchers to study both the mosquito host and its associated microbiota. Although most of these studies have been descriptive, they have led to a broad description of the bacterial communities hosted by mosquito populations. This review describes key advances and progress in the field of the mosquito microbiota research while also encompassing other microbes and the environmental factors driving their composition and diversity. The discussion includes recent findings on the microbiota functional roles and underlines their interactions with the host biology and pathogen transmission. Insight into the ecology of multipartite interactions, we consider that conferring the term holobiont to the mosquito and its microbiota is useful to get a comprehensive understanding of the vector pathosystem functioning so as to be able to develop innovative and efficient novel vector control strategies. The online version of this article (10.1186/s40168-018-0435-2) contains supplementary material, which is available to authorized users.
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影响因子：
3.7
作者：
Apte-Deshpande A;Paingankar M;Gokhale MD;Deobagkar DN
通讯作者：
Deobagkar DN
DOI：
10.3390/v7020820
发表时间：
2015-02-17
期刊：
Viruses
影响因子：
--
作者：
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通讯作者：
Olson KE
影响因子：
5.1
作者：
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通讯作者：
Taylor, Michael W.
影响因子：
3.8
作者：
Audsley, Michelle D.;Ye, Yixin H.;McGraw, Elizabeth A.
通讯作者：
McGraw, Elizabeth A.
DOI：
10.1073/pnas.1412984112
发表时间：
2015-01-13
影响因子：
11.1
作者：
Carissimo, Guillaume;Pondeville, Emilie;Vernick, Kenneth D.
通讯作者：
Vernick, Kenneth D.