Interspecies transmission and host restriction of avian H5N1 influenza virus.
Interspecies transmission and host restriction of avian H5N1 influenza virus.
复制标题
种间传播和宿主对鸟类H5N1流感病毒的限制。
DOI:
10.1007/s11427-009-0062-z
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发表时间:
2009-05
期刊:
影响因子:
--
通讯作者:
Gao GF
中科院分区:
文献类型:
--
作者:
Liu D;Liu X;Yan J;Liu WJ;Gao GF
Long-term endemicity of avian H5N1 influenza virus in poultry and continuous sporadic human infections in several countries has raised the concern of another potential pandemic influenza. Suspicion of the avian origin of the previous pandemics results in the close investigation of the mechanism of interspecies transmission. Entry and fusion is the first step for the H5N1 influenza virus to get into the host cells affecting the host ranges. Therefore receptor usage study has been a major focus for the last few years. We now know the difference of the sialic acid structures and distributions in different species, even in the different parts of the same host. Many host factors interacting with the influenza virus component proteins have been identified and their role in the host range expansion and interspecies transmission is under detailed scrutiny. Here we review current progress in the receptor usage and host factors.
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影响因子:
14.9
作者:
通讯作者:
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影响因子:
3.8
作者:
Burgui, I;Aragón, T;Nieto, A
通讯作者:
Nieto, A
影响因子:
14.9
作者:
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通讯作者:
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通讯作者:
Webster, RG
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64.8
作者:
ALMOND, JW
通讯作者:
ALMOND, JW