Hypothalamic Ceramides and the Ovarian Sympathetic System: At the Crossroads of Obesity and Puberty.
Hypothalamic Ceramides and the Ovarian Sympathetic System: At the Crossroads of Obesity and Puberty.
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DOI:
10.1016/j.cmet.2020.11.012
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发表时间:
2021-01-05
期刊:
影响因子:
29
通讯作者:
Balasubramanian R
中科院分区:
文献类型:
--
作者:
Stamou MI;Balasubramanian R
Childhood obesity has been linked to early puberty in girls but the mechanism(s) by which overnutrition triggers pubertal onset remain unclear. In a recent issue of Cell Metabolism, implicate a non-canonical central ceramide to ovarian sympathetic innervation pathway as a novel mediator of obesity-induced pubertal acceleration in female rats.
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