Neurological soft signs in individuals with pathological gambling.

Neurological soft signs in individuals with pathological gambling.
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DOI:
10.1371/journal.pone.0060885
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发表时间:
2013
期刊:
影响因子:
3.7
通讯作者:
Pitman RK
Pitman RK
中科院分区:
综合性期刊3区
文献类型:
--
作者:
Elman I;Gurvits TV;Tschibelu E;Spring JD;Lasko NB;Pitman RK

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在许多神经精神综合征(包括化学成瘾)中发现了增加的神经软征(NSS)。本研究探讨了行为成瘾中与知觉运动和视觉空间加工相关的NSS,即,病态赌博(PG)与心理健康的人相比,病态赌徒在复制二维和三维图形、在背景噪音中识别物体以及在道路图测试中定位空间的能力明显较差。结果表明,PG与微妙的大脑皮质异常。需要进一步的前瞻性临床研究来解决NSS的起源和时间顺序(例如,早于或跟随PG的发展)以及它们对治疗干预的反应和/或它们预测这种反应的能力。
Increased neurological soft signs (NSSs) have been found in a number of neuropsychiatric syndromes, including chemical addiction. The present study examined NSSs related to perceptual-motor and visuospatial processing in a behavioral addiction viz., pathological gambling (PG). As compared to mentally healthy individuals, pathological gamblers displayed significantly poorer ability to copy two- and three-dimensional figures, to recognize objects against a background noise, and to orient in space on a road-map test. Results indicated that PG is associated with subtle cerebral cortical abnormalities. Further prospective clinical research is needed to address the NSSs' origin and chronology (e.g., predate or follow the development of PG) as well as their response to therapeutic interventions and/or their ability to predict such a response.
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