The effects of Lactobacillus pentosus strain b240 and appropriate physical training on salivary secretory IgA levels in elderly adults with low physical fitness: a randomized, double-blind, placebo-controlled trial.
The effects of Lactobacillus pentosus strain b240 and appropriate physical training on salivary secretory IgA levels in elderly adults with low physical fitness: a randomized, double-blind, placebo-controlled trial.
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DOI：
10.3164/jcbn.13-62
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发表时间：
2014-01
影响因子：
2.4
通讯作者：
Kuno S
中科院分区：
文献类型：
--
作者：
Shimizu K;Sato H;Suga Y;Yamahira S;Toba M;Hamuro K;Kakumoto K;Kohda N;Akama T;Kono I;Kuno S
该研究的目的是评估戊糖乳杆菌b240菌株（b240）摄入量和适当的体能训练对体质较差的老年人唾液分泌型免疫球蛋白A分泌的影响。体质较差（每日步数低于 3,500 步）的老年人被分为 2 组：b240 摄入+运动组（b240 组）和安慰剂摄入+运动组（安慰剂组）。每个受试者持续摄入 b240 或安慰剂并进行中等强度的阻力运动 12 周。在干预开始前以及干预开始后 4、8 和 12 周，每个受试者都接受了唾液采样。干预前后进行体能测试和步数测量。我们的结果显示，在 b240/安慰剂摄入期间，57 名受试者的分泌性免疫球蛋白 A 分泌量，b240 组显着高于安慰剂组 (p<0.05)。 2组干预前后体能测试无明显变化。两组干预后每日步行量均显着增加（p<0.05）。这些结果表明，在体力活动和身体素质较低的老年人中，摄入 b240 并进行适当的体育锻炼可以提高唾液分泌型免疫球蛋白 A 的分泌。
The purpose of the study was to evaluate the effects of Lactobacillus pentosus strain b240 (b240) intake and appropriate physical training on salivary secretory immunoglobulin A secretion in elderly adults with low physical fitness. Elderly adults with low physical fitness (daily step count below 3,500 steps) were divided into 2 groups: a b240 intake + exercise group (b240 group) and a placebo intake + exercise group (placebo group). Each subject continued intake of b240 or placebo and moderate-intensity resistance exercise for 12 weeks. Before and 4, 8, and 12 weeks after the start of intervention, each subject underwent saliva sampling. Before and after intervention, physical fitness tests and step count were measured. Our results showed that secretory immunoglobulin A secretion in 57 subjects during the b240/placebo intake period was significantly greater in the b240 group than in the placebo group (p<0.05). There were no significant changes in physical fitness tests before and after intervention in the 2 groups. The daily amount of walking increased significantly after intervention in both groups (p<0.05). These results suggest that in elderly adults with low physical activity and fitness, intake of b240 with appropriate physical exercise elevate salivary secretory immunoglobulin A secretion.
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影响因子：
4.4
作者：
Shimosato, T;Tohno, M;Saito, T
通讯作者：
Saito, T
影响因子：
1.2
作者：
OKADA, S;DAENGSUBHA, W;KOZAKI, M
通讯作者：
KOZAKI, M
DOI：
10.1111/j.1600-0838.2007.00642.x
发表时间：
2008-06-01
影响因子：
4.1
作者：
Kimura, F.;Aizawa, K.;Kono, I.
通讯作者：
Kono, I.
影响因子：
3
作者：
Klentrou, P;Cieslak, T;Plyley, M
通讯作者：
Plyley, M
影响因子：
2.1
作者：
Boudreau, J.;Hoffman-Goetz, L.
通讯作者：
Hoffman-Goetz, L.