American ginseng: research developments, opportunities, and challenges.

American ginseng: research developments, opportunities, and challenges.
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DOI:
10.5142/jgr.2011.35.3.368
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发表时间:
2011-09
影响因子:
6.3
通讯作者:
Punja ZK
Punja ZK
中科院分区:
医学2区
文献类型:
--
作者:
Punja ZK

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西洋参(Panax ququiefolius L.)在美国和加拿大的一些地区种植,并因其促进健康的特性而上市。虽然北美种植这种植物已有100多年的历史,但仍有许多挑战需要解决。本文描述了种植者目前使用的生产方法,并讨论了这种有价值的植物研究面临的挑战和机遇。这些研究包括药理活性、物种内的遗传多样性、当前种植植物的遗传改良、基因表达的分子特征以及影响植物生产力的疾病的管理。综述了这些领域的研究现状,并总结了需要进一步研究的领域。更多的研究将阐明活性化合物的性质及其临床效果,以及活性成分生物合成的分子基础,并提供更均匀的遗传物质以及改善植物生长,并有可能减少病原体造成的损失。
American ginseng (Panax quinquefolius L.) is grown in some regions of the USA and Canada and marketed for its health promoting attributes. While cultivation of this plant species has taken place in North America for over 100 years, there are many challenges that need to be addressed. In this article, the current production method used by growers is described and the challenges and opportunities for research on this valuable plant are discussed. These include studies on pharmacological activity, genetic diversity within the species, genetic improvement of currently grown plants, molecular characterization of gene expression, and management of diseases affecting plant productivity. The current research developments in these areas are reviewed and areas requiring further work are summarized. Additional research should shed light on the nature of the bioactive compounds and their clinical effects, and the molecular basis of active ingredient biosynthesis, and provide more uniform genetic material as well as improved plant growth, and potentially reduce losses due to pathogens.
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