Dosing Exercise: Is More Really Better for Obesity-Related Outcomes?
Dosing Exercise: Is More Really Better for Obesity-Related Outcomes?
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DOI：
10.1002/oby.22330
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发表时间：
2018-11
期刊：
影响因子：
--
通讯作者：
Malin SK
中科院分区：
文献类型：
--
作者：
Malin SK
关于影响肥胖相关疾病（如2型糖尿病和代谢综合征）所需的运动剂量（如强度、持续时间和频率）有很多争论。通常情况下，高强度的运动与有氧健身水平的提高、胰岛素敏感性的提高、良好的血脂状况和低体脂有关。然而，在过去的二十年里，一些团体挑战了“越多越好”的教条，并且临床试验试图确定运动对肥胖个体产生代谢益处的剂量（1-4）。本期《肥胖》杂志介绍了在受控条件下运动剂量对身体成分影响的新研究(5)。Cowan等人(5)测试了能量匹配治疗下的运动量（千卡/次）和强度（% vo2峰值）对肥胖成人脂肪组织和骨骼肌的影响，以及血糖、循环脂质和胰岛素抵抗的相关变化。参与者为中年男性和女性，随机分为：对照组（无运动）、低量低强度（LALI）、高量低强度（HALI）或高量高强度（HAHI）基于跑步机的运动，每周5天，持续24周。根据vo2 -心率的关系来确定各组之间的能量消耗，并利用磁共振成像（MRI）来确定腹部脂肪和骨骼肌。在整个干预过程中，使用加速度计评估非运动性身体活动，并通过食物记录监测饮食。总的来说，与对照组相比，皮下脂肪和内脏脂肪在不同运动剂量下都有所减少，并且身体下部（但不是上部）的骨骼肌得到了保留。
There is much debate regarding the exercise dose (eg intensity, duration, and frequency) required to impact obesity related diseases such as type 2 diabetes and metabolic syndrome. Typically, a high amount of exercise is associated with elevated aerobic fitness, heightened insulin sensitivity, favorable blood lipid profiles, and low body fat. However, groups over the last two decades have challenged the dogma that “more is better”, and clinical trials have sought to determine the dose by which exercise yields metabolic benefit in individuals with obesity (1-4). This issue of Obesity presents novel work examining the impact of exercise dose on body composition under controlled conditions (5).Cowan et al.(5) tested the effect of exercise amount (kilocalories/session) and intensity (% VO2peak) under energy-matched treatments on adipose tissue and skeletal muscle in adults with obesity and related these changes in blood glucose, circulating lipids, and insulin resistance. Participants were middleaged men and women that were randomized to: control (no exercise), low amount low intensity (LALI), high amount low intensity (HALI), or high amount high intensity (HAHI) treadmill based exercise 5 d/wk under supervision for 24 weeks. Energy expenditure was clamped between groups based on VO2-heart rate relationships, and magnetic resonance imaging (MRI) was utilized to determine abdominal adiposity as well as skeletal muscle. Non-exercise physical activity was assessed using accelerometers and diet was monitored via food records throughout the intervention. Overall, subcutaneous and visceral fat were reduced comparably across exercise doses compared with control, and lower, but not upper, body skeletal muscle was preserved.
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影响因子：
6.9
作者：
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通讯作者：
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DOI：
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发表时间：
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发表时间：
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发表时间：
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影响因子：
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作者：
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作者：
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