Neural correlates of familiarity-based associative retrieval.

Neural correlates of familiarity-based associative retrieval.
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DOI:
10.1016/j.neuropsychologia.2010.06.010
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发表时间:
2010-08
期刊:
影响因子:
2.6
通讯作者:
Giovanello KS
Giovanello KS
中科院分区:
心理学3区
文献类型:
--
作者:
Ford JH;Verfaellie M;Giovanello KS

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本研究比较了复合(unitized)刺激和无关(non-unitized)刺激的联想提取的神经相关。虽然联想识别是几乎相同的化合物和不相关的对,这些不同的对类型的准确识别与激活不同的区域内内侧颞叶(MTL)。识别以前提出的复合词与左周围的活动,而识别无关的词对与左海马体的活动。这些结果提供的证据表明,嗅周皮层介导的熟悉为基础的联想记忆的刺激在编码单位,而海马是所需的回忆为基础的联想记忆。
The current study compared the neural correlates of associative retrieval of compound (unitized) stimuli and unrelated (non-unitized) stimuli. Although associative recognition was nearly identical for compounds and unrelated pairs, accurate recognition of these different pair types was associated with activation in distinct regions within the medial temporal lobe (MTL). Recognition of previously presented compound words was associated with left perirhinal activity, whereas recognition of unrelated word pairs was associated with activity in left hippocampus. These results provide evidence that perirhinal cortex mediates familiarity-based associative memory of stimuli unitized at encoding, while the hippocampus is required for recollection-based associative memory.
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