Frequency following responses and rate change complexes in cochlear implant users.
Frequency following responses and rate change complexes in cochlear implant users.
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DOI：
10.1016/j.heares.2021.108200
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发表时间：
2021-05
期刊：
影响因子：
2.8
通讯作者：
Wouters J
中科院分区：
文献类型：
--
作者：
Gransier R;Guérit F;Carlyon RP;Wouters J
在人工耳蜗使用者中，频率跟随反应可以在没有刺激伪影的情况下获得。耳蜗使用者的脉搏变化可诱发听觉变化复合体。电生理反应可以潜在地用于评估在人工耳蜗使用者的速率处理。基于频率的音高感知和频率辨别的上限在人工耳蜗（CI）使用者之间可能存在很大差异。造成这种差异的一个潜在原因是电刺激听觉通路的时间编码存在生物学限制，这可能是电刺激本身和/或与听力损失相关的退化过程所固有的。电生理测量，如电诱发频率跟随反应（eFFR）和听觉变化复核（eACC），可能为在电刺激听觉通路中脑干和皮层水平上的时间加工限制提供有价值的见解。在不受刺激影响的情况下获得这些神经反应是具有挑战性的，尤其是当神经反应与刺激速率相锁时，就像eFFR的情况一样。在本研究中，我们研究了在单极结构下，在没有刺激伪影的情况下，在94至196脉冲/秒（pps）的刺激速率范围内测量effr的可行性，在36至108%的脉冲速率变化范围内测量eACCs。采用高采样率脑电系统测量了5名CI使用者的电生理反应，并采用线性插值法去除脑电中的刺激伪影。通过这种方法，我们能够测量脉冲速率高达162 pps的effr和不同速率变化的eacc。我们的研究结果表明，测量电生理反应是可行的，没有刺激伪影，这可能被用作CI用户的频率和音高处理的神经关联。
Frequency following responses can be obtained free from stimulation artifacts in cochlear implant users. Auditory change complexes can be evoked with pulse rate changes in cochlear implant users. Electrophysiological responses can potentially be used for the assessment of rate processing in cochlear implant user. The upper limit of rate-based pitch perception and rate discrimination can differ substantially across cochlear implant (CI) users. One potential reason for this difference is the presence of a biological limitation on temporal encoding in the electrically-stimulated auditory pathway, which can be inherent to the electrical stimulation itself and/or to the degenerative processes associated with hearing loss. Electrophysiological measures, like the electrically-evoked frequency following response (eFFR) and auditory change complex (eACC), could potentially provide valuable insights in the temporal processing limitations at the level of the brainstem and cortex in the electrically-stimulated auditory pathway. Obtaining these neural responses, free from stimulation artifacts, is challenging, especially when the neural response is phase-locked to the stimulation rate, as is the case for the eFFR. In this study we investigated the feasibility of measuring eFFRs, free from stimulation artifacts, to stimulation rates ranging from 94 to 196 pulses per second (pps) and eACCs to pulse rate changes ranging from 36 to 108%, when stimulating in a monopolar configuration. A high-sampling rate EEG system was used to measure the electrophysiological responses in five CI users, and linear interpolation was applied to remove the stimulation artifacts from the EEG. With this approach, we were able to measure eFFRs for pulse rates up to 162 pps and eACCs to the different rate changes. Our results show that it is feasible to measure electrophysiological responses, free from stimulation artifacts, that could potentially be used as neural correlates for rate and pitch processing in CI users.
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MEG揭示的对听觉频率遵循响应的皮质贡献。
影响因子：
16.6
作者：
Coffey EB;Herholz SC;Chepesiuk AM;Baillet S;Zatorre RJ
通讯作者：
Zatorre RJ
影响因子：
3.7
作者：
Green, Tim;Faulkner, Andrew;Rosen, Stuart
通讯作者：
Rosen, Stuart
DOI：
10.1109/tnsre.2016.2622979
发表时间：
2017-08-01
影响因子：
4.9
作者：
Deprez, Hanne;Gransier, Robin;Moonen, Marc
通讯作者：
Moonen, Marc
较低（93-109 Hz）的包络膜响应的注意调制，但不是更高（217-233 Hz）调制速率。
DOI：
10.1007/s10162-017-0641-9
发表时间：
2018-03
期刊：
Journal of the Association for Research in Otolaryngology : JARO
影响因子：
--
作者：
Holmes E;Purcell DW;Carlyon RP;Gockel HE;Johnsrude IS
通讯作者：
Johnsrude IS
影响因子：
4.6
作者：
Gransier R;Carlyon RP;Wouters J
通讯作者：
Wouters J