Salivary testosterone and cortisol in disruptive children: relationship to aggressive, hyperactive, and internalizing behaviors.

Salivary testosterone and cortisol in disruptive children: relationship to aggressive, hyperactive, and internalizing behaviors.
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破坏性儿童的唾液睾酮和皮质醇:与攻击性、过度活跃和内化行为的关系。

DOI:
10.1097/00004583-199410000-00013
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发表时间:
1994
影响因子:
13.3
通讯作者:
Kolko,DJ
Kolko,DJ
中科院分区:
医学1区
文献类型:
--
作者:
Scerbo,AS;Kolko,DJ

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目的检验预测基础唾液睾酮和皮质醇分别与反社会行为和内化行为有关,皮质醇调节睾酮-攻击行为的关系。方法对40名7 - 14岁的破坏性儿童(父母、老师和临床工作人员对这些儿童的攻击性、注意力不集中/过度活跃和内化行为进行评分)进行唾液样本检测,以测定其睾酮和皮质醇水平。结果睾酮与员工评定的攻击性行为、皮质醇与父母评定的内化行为呈显著正相关。皮质醇与员工评价的注意力不集中/过度活动之间存在显著的负相关。睾酮和皮质醇之间没有相互作用。这些结果与年龄、种族背景、身高、体重、诊断或药物状况无关。结论:结果表明,在一组破坏性儿童中,睾酮与观察到的攻击性、皮质醇与情绪行为之间存在适度的关系。在这个人群中,皮质醇并没有调节睾丸激素与攻击性的关系。
ObjectiveTo test predictions that basal salivary testosterone and cortisol are related to antisocial and internalizing behaviors, respectively, and that cortisol moderates the testosterone-aggression relationship.MethodSaliva samples were assayed to determine testosterone and cortisol levels in 40 clinic-referred disruptive children (aged 7 through 14 years) who were rated on aggression, inattention/overactivity, and internalizing behavior by parents, teachers, and clinic staff members.ResultsResults indicated significant positive relationships between testosterone and staff-rated aggression and between cortisol and parent-rated internalizing behavior. A significant negative relationship was found between cortisol and staff-rated inattention/overactivity. No interactions between testosterone and cortisol were found. These results were maintained regardless of age, racial background, height, weight, diagnosis, or medication status.ConclusionsResults suggest moderate relationships between testosterone and observed aggression, and between cortisol and emotional behaviors, in a group of disruptive children. Cortisol did not moderate the testosterone-aggression relationship in this population.
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