Workplace standing time and the incidence of obesity and type 2 diabetes: a longitudinal study in adults.
Workplace standing time and the incidence of obesity and type 2 diabetes: a longitudinal study in adults.
复制标题
DOI：
10.1186/s12889-015-1353-x
复制
发表时间：
2015-02-10
影响因子：
4.5
通讯作者：
Bouchard C
中科院分区：
文献类型：
--
作者：
Chaput JP;Saunders TJ;Tremblay MS;Katzmarzyk PT;Tremblay A;Bouchard C
人们越来越认识到，站立是解决长时间坐着的简单方法。然而，目前尚不清楚工作场所站立时间是否与慢性病发病率降低有关。本研究的目的是探讨成人工作场所站立时间与超重/肥胖 (OW/OB) 和糖耐量受损/2 型糖尿病 (IGT/T2D) 发生率之间的关联。魁北克家庭研究（加拿大）对 293 名年龄在 18 岁至 65 岁之间的参与者进行了纵向分析，平均随访时间为 6 年。在基线和随访时收集了有关自我报告的职业站立时间以及几个协变量的信息。结果测量包括 OW/OB（即体重指数≥25 kg/m2）和 IGT/T2D（即负荷后 2 小时血浆葡萄糖水平≥7.8 mmol/L）的发展。 6年随访期间OW/OB和IGT/T2D的发生率分别为17.4%和12.6%。在职业站立时间与结果指标的制定之间观察到显着的负相关。然而，在调整年龄、性别、吸烟习惯、家庭年总收入、每日热量摄入和次最大工作能力后，这种关联不再显着。在年龄和性别调整后的逻辑回归分析中，在站立时间和结果变量水平上观察到显着的负线性趋势。然而，在进一步调整其他协变量后，这些关联不再显着。最后，我们观察到站立时间从基线到第 6 年的变化与结果指标的制定显着相关，成人报告随访时站立时间减少的发病率较高。然而，在调整协变量后，这些关联变得不显着。较长的职业站立时间本身并不足以预防成人 OW/OB 和 IGT/T2D 的发生。未来需要努力更好地了解全天站立时间较长对预防慢性病的潜在好处。
It is increasingly recognized that standing represents a simple solution to extended periods of sitting. However, it is currently unknown whether workplace standing time is prospectively associated with a lower incidence of chronic diseases. The objective of this study was to examine the association between workplace standing time and the incidence of overweight/obesity (OW/OB) and impaired glucose tolerance/type 2 diabetes (IGT/T2D) in adults. A longitudinal analysis from the Quebec Family Study (Canada) was conducted on 293 participants, aged 18 to 65 years, followed for a mean of 6 years. Information on self-reported occupational standing time as well as several covariates was collected at both baseline and follow-up. Outcome measures included the development of OW/OB (i.e. body mass index ≥25 kg/m2) and IGT/T2D (i.e. 2-h postload plasma glucose level ≥7.8 mmol/L). The incidence rates of OW/OB and IGT/T2D over the 6-year follow-up period were 17.4% and 12.6%, respectively. Significant negative associations were observed between the amount of occupational standing time and the development of outcome measures. However, the associations were no longer significant after adjustment for age, sex, smoking habits, total annual family income, daily caloric intake, and submaximal working capacity. In age- and sex-adjusted logistic regression analysis, significant negative linear trends were observed across levels of standing time and the outcome variables. However, the associations were no longer significant after further adjustment for the other covariates. Finally, we observed that the change in standing time from baseline to year 6 was significantly associated with the development of outcome measures, with higher incidence rates in adults reporting a reduction in standing time at follow-up. However, the associations became non-significant after adjustment for covariates. Greater occupational standing time is not sufficient in and of itself to prevent the development of OW/OB and IGT/T2D in adults. Future efforts are needed to better understand the potential benefits of higher amounts of standing time throughout the day on the prevention of chronic diseases.
登录
查看更多内容
影响因子：
3.7
作者：
Saunders TJ;Tremblay MS;Mathieu MÈ;Henderson M;O'Loughlin J;Tremblay A;Chaput JP;QUALITY cohort research group
通讯作者：
QUALITY cohort research group
影响因子：
8.8
作者：
Chaput, Jean-Philippe;Perusse, Louis;Despres, Jean-Pierre;Tremblay, Angelo;Bouchard, Claude
通讯作者：
Bouchard, Claude
影响因子：
16.2
作者：
Dunstan DW;Kingwell BA;Larsen R;Healy GN;Cerin E;Hamilton MT;Shaw JE;Bertovic DA;Zimmet PZ;Salmon J;Owen N
通讯作者：
Owen N
影响因子：
5
作者：
Matthews, Charles E.;Chen, Kong Y.;Troiano, Richard P.
通讯作者：
Troiano, Richard P.
影响因子：
7.7
作者：
Hamilton, Marc T.;Hamilton, Deborah G.;Zderic, Theodore W.
通讯作者：
Zderic, Theodore W.