Spread of Cryptococcus gattii in British Columbia, Canada, and detection in the Pacific Northwest, USA.
Spread of Cryptococcus gattii in British Columbia, Canada, and detection in the Pacific Northwest, USA.
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DOI：
10.3201/eid1301.060827
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发表时间：
2007-01
影响因子：
11.8
通讯作者：
Bartlett KH
中科院分区：
文献类型：
--
作者：
MacDougall L;Kidd SE;Galanis E;Mak S;Leslie MJ;Cieslak PR;Kronstad JW;Morshed MG;Bartlett KH
1999年在加拿大不列颠哥伦比亚省（BC）温哥华岛出现的格特隐球菌，在2003-2005年期间在潜伏期内未前往温哥华岛的3个人和8只动物中检测到;在温哥华岛以外的地区检测到阳性环境样本。在BC发现的所有临床和环境分离株的基因型与温哥华岛菌株一致。此外，在华盛顿的3只猫和俄勒冈州的2人中检测到本地获得性。俄勒冈州分离株的分子特征与在不列颠哥伦比亚省和华盛顿发现的不同。虽然太平洋西北部的一些小气候与温哥华岛相似，但C.岛外环境中的格特氏菌浓度通常较低，未与温哥华岛接触的人间病例没有继续发生。这表明C. gattii不得在岛外永久定居。
Cryptococcus gattii, emergent on Vancouver Island, British Columbia (BC), Canada, in 1999, was detected during 2003–2005 in 3 persons and 8 animals that did not travel to Vancouver Island during the incubation period; positive environmental samples were detected in areas outside Vancouver Island. All clinical and environmental isolates found in BC were genotypically consistent with Vancouver Island strains. In addition, local acquisition was detected in 3 cats in Washington and 2 persons in Oregon. The molecular profiles of Oregon isolates differed from those found in BC and Washington. Although some microclimates of the Pacific Northwest are similar to those on Vancouver Island, C. gattii concentrations in off-island environments were typically lower, and human cases without Vancouver Island contact have not continued to occur. This suggests that C. gattii may not be permanently colonized in off-island locations.
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影响因子：
5
作者：
KWONCHUNG, KJ;BENNETT, JE
通讯作者：
BENNETT, JE
影响因子：
11.8
作者：
Chen, S;Sorrell, T;Byth, K
通讯作者：
Byth, K
DOI：
10.1073/pnas.0402981101
发表时间：
2004-12-07
影响因子：
11.1
作者：
Kidd, SE;Hagen, F;Meyer, W
通讯作者：
Meyer, W
影响因子：
5
作者：
BENNETT, JE;KWONCHUNG, KJ;HOWARD, DH
通讯作者：
HOWARD, DH
影响因子：
2.9
作者：
O'Brien, CR;Krockenberger, MB;Malik, R
通讯作者：
Malik, R