Recent Trends in Covalent and Metal Organic Frameworks for Biomedical Applications.

Recent Trends in Covalent and Metal Organic Frameworks for Biomedical Applications.
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DOI:
10.3390/nano8110916
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发表时间:
2018-11-07
期刊:
Nanomaterials (Basel, Switzerland)
影响因子:
--
通讯作者:
Yassin A
Yassin A
中科院分区:
其他
文献类型:
--
作者:
Chedid G;Yassin A

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材料科学已经取得了很大的进步和发展。新型材料的发现引发了对其性质的研究,随后应用范围从分离,催化,光电子学,传感,药物输送和生物医学,以及不同科学领域的许多其他用途。金属有机骨架(MOFs)和共价有机骨架(COFs)是相对新型的材料,具有高表面积和永久孔隙率,在此类应用中显示出巨大的前景。本研究旨在介绍COFs和MOFs在生物医学应用中的最新工作,并研究该领域可能面临的一些挑战和未来的发展方向。本文综述了它们的合成,以及它们作为药物递送系统(DDS)在非药物递送治疗以及生物传感和诊断中的应用。
Materials science has seen a great deal of advancement and development. The discovery of new types of materials sparked the study of their properties followed by applications ranging from separation, catalysis, optoelectronics, sensing, drug delivery and biomedicine, and many other uses in different fields of science. Metal organic frameworks (MOFs) and covalent organic frameworks (COFs) are a relatively new type of materials with high surface areas and permanent porosity that show great promise for such applications. The current study aims at presenting the recent work achieved in COFs and MOFs for biomedical applications, and to examine some challenges and future directions which the field may take. The paper herein surveys their synthesis, and their use as Drug Delivery Systems (DDS), in non-drug delivery therapeutics and for biosensing and diagnostics.
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