Potential metabolic and genetic interaction among viruses, methanogen and methanotrophic archaea, and their syntrophic partners.
Potential metabolic and genetic interaction among viruses, methanogen and methanotrophic archaea, and their syntrophic partners.
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病毒，甲烷原和甲烷性古细菌及其综合伴侣之间的潜在代谢和遗传相互作用。
DOI：
10.1038/s43705-022-00135-2
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发表时间：
2022-06-28
期刊：
影响因子：
--
通讯作者：
Zhang, Rui
中科院分区：
文献类型：
--
作者：
Wang, Long;Wang, Yinzhao;Huang, Xingyu;Ma, Ruijie;Li, Jiangtao;Wang, Fengping;Jiao, Nianzhi;Zhang, Rui
缺氧生态系统中甲烷的代谢主要由产甲烷菌和甲烷氧化古菌（MMA）介导，它们是全球碳循环的关键参与者。病毒在调节宿主命运和生态功能方面起着至关重要的作用。然而，我们对MMA病毒的分布和多样性及其与宿主的相互作用的了解相当有限。本研究通过从多种环境中搜索含有mcrA（甲基辅酶M还原酶α-亚基编码基因）的宏基因组，检索到140个可能感染产甲烷菌或甲烷氧化古菌的病毒操作分类单位（votu）。预测4个MMA vOTUs（3个感染甲烷杆菌目，1个感染甲烷球菌目）可跨区域感染硫酸盐还原菌。通过促进硫的同化还原，MMA病毒可能会增加其宿主在硫酸盐耗尽的缺氧生态系统中的适应性，并从含硫氨基酸半胱氨酸的合成中获益。此外，MMA病毒促进细胞间的聚集可能对病毒和宿主都有好处，分别通过提高感染性和环境抗逆性。我们的研究结果表明，病毒在产甲烷菌和甲烷氧化古菌的生态和环境适应中具有潜在的作用。
The metabolism of methane in anoxic ecosystems is mainly mediated by methanogens and methane-oxidizing archaea (MMA), key players in global carbon cycling. Viruses are vital in regulating their host fate and ecological function. However, our knowledge about the distribution and diversity of MMA viruses and their interactions with hosts is rather limited. Here, by searching metagenomes containing mcrA (the gene coding for the α-subunit of methyl-coenzyme M reductase) from a wide variety of environments, 140 viral operational taxonomic units (vOTUs) that potentially infect methanogens or methane-oxidizing archaea were retrieved. Four MMA vOTUs (three infecting the order Methanobacteriales and one infecting the order Methanococcales) were predicted to cross-domain infect sulfate-reducing bacteria. By facilitating assimilatory sulfur reduction, MMA viruses may increase the fitness of their hosts in sulfate-depleted anoxic ecosystems and benefit from synthesis of the sulfur-containing amino acid cysteine. Moreover, cell-cell aggregation promoted by MMA viruses may be beneficial for both the viruses and their hosts by improving infectivity and environmental stress resistance, respectively. Our results suggest a potential role of viruses in the ecological and environmental adaptation of methanogens and methane-oxidizing archaea.
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影响因子：
7.7
作者：
Beghini F;McIver LJ;Blanco-Míguez A;Dubois L;Asnicar F;Maharjan S;Mailyan A;Manghi P;Scholz M;Thomas AM;Valles-Colomer M;Weingart G;Zhang Y;Zolfo M;Huttenhower C;Franzosa EA;Segata N
通讯作者：
Segata N
高度分层的硫化矿尾矿中病毒群落与深度相关的变异性
影响因子：
15.5
作者：
Gao, Shao-Ming;Schippers, Axel;Huang, Li-Nan
通讯作者：
Huang, Li-Nan
DOI：
10.1099/13500872-145-5-1263
发表时间：
1999-05-01
期刊：
MICROBIOLOGY-UK
影响因子：
--
作者：
Guan, S;Bastin, DA;Verma, NK
通讯作者：
Verma, NK
影响因子：
56.9
作者：
Hallam, SJ;Putnam, N;DeLong, EF
通讯作者：
DeLong, EF
影响因子：
14.9
作者：
Couvin D;Bernheim A;Toffano-Nioche C;Touchon M;Michalik J;Néron B;Rocha EPC;Vergnaud G;Gautheret D;Pourcel C
通讯作者：
Pourcel C