Association of alcohol use and multimorbidity among adults aged 40 years and above in rural South Africa.

Association of alcohol use and multimorbidity among adults aged 40 years and above in rural South Africa.
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DOI:
10.1038/s41598-023-35018-6
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发表时间:
2023-05-14
期刊:
影响因子:
4.6
通讯作者:
--
中科院分区:
综合性期刊3区
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我们评估了南非农村地区40岁及以上成年人中报告的酒精使用的患病率及其与多发病的相关性。研究结果可能会为酒精干预措施在慢性病预防和治疗中的整合提供信息。我们分析了2014年11月至2015年11月期间在阿金库尔健康和人口监测系统内嵌套的INDEPTH社区(HAALSI)进行的第一波非洲健康与老龄化纵向研究的数据(n = 5059)。我们计算了描述性统计量并进行了单变量分析,以确定与多发性骨髓瘤独立相关的因素。年龄、体重指数、教育、性别和家庭财富状况以及单变量分析中p值< 0.20的变量被纳入多变量修正泊松回归模型。最终模型中p值< 0.05的任何因素均被认为具有统计学显著性。第一波HAALSI由5059名40岁及以上的参与者完成,其中包括2714名(53.6%)女性。报告的曾经饮酒的患病率为44.6%(n = 2253),其中51.9%(n = 1171)报告在过去30天内饮酒。HIV多重感染率为59.6%(3014/5059),非HIV多重感染率为52.5%(2657/5059)。饮酒与所有参与者的HIV多重感染相关(RR:1.05,95%CI:1.02-1.08),男性(RR:1.05,95%CI:1.00-1.10)和女性(RR:1.06,95%CI:1.02-1.11)分别与之相关。同样,在所有参与者中,饮酒与无艾滋病毒的多发病相关(RR:1.05,95% CI:1.02-1.09),男性(RR:1.06,95% CI:1.00-1.12)和女性(RR:1.06,95% CI:1.01-1.11)分别相关。在南非东北部农村的老年人中,报告的饮酒很常见,与艾滋病毒多发病和无艾滋病毒的多发病有关。有必要整合筛选,简短的干预措施,并在南非现有的预防和治疗多发性硬化症的酒精治疗转诊。
We assessed the prevalence of reported alcohol use and its association with multimorbidity among adults aged 40 years and above in a rural, transitioning South African setting. Findings could potentially inform alcohol interventions integration in the prevention and treatment of chronic conditions. We analysed data from the first wave of The Health and Ageing in Africa—a longitudinal Study in an INDEPTH community (HAALSI) nested within the Agincourt Health and Demographic Surveillance Systems, conducted between November 2014 and November 2015 (n = 5059). We computed descriptive statistics and performed univariate analysis to determine factors independently associated with multimorbidity. Age, Body Mass Index, education, sex, and household wealth status and variables with a p-value < 0.20 in univariate analysis were included in multivariable Modified Poisson regression models. Any factors with a p-value of < 0.05 in the final models were considered statistically significant. The first wave of HAALSI was completed by 5059 participants aged 40 years and above and included 2714 (53.6%) females. The prevalence of reported ever alcohol use was 44.6% (n = 2253) and of these 51.9% (n = 1171) reported alcohol use in the last 30 days. The prevalence of HIV multimorbidity was 59.6% (3014/5059) and for multimorbidity without HIV 52.5% (2657/5059). Alcohol use was associated with HIV multimorbidity among all participants (RR: 1.05, 95% CI: 1.02–1.08), and separately for males (RR: 1.05, 95% CI: 1.00–1.10) and females (RR: 1.06, 95%CI: 1.02–1.11). Similarly, alcohol use was associated with multimorbidity without HIV among all participants (RR: 1.05, 95% CI: 1.02–1.09), and separately for males (RR: 1.06, 95% CI: 1.00–1.12) and females (RR: 1.06, 95% CI: 1.01–1.11). Reported alcohol use was common and associated with HIV multimorbidity and multimorbidity without HIV among older adults in rural northeast South Africa. There is a need to integrate Screening, Brief Interventions, and Referral for alcohol Treatment in the existing prevention and treatment of multimorbidity in South Africa.
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发表时间: 2019-07-15
期刊: ADDICTION
影响因子: 6
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