Heavy drinking among individuals with HIV: who drinks despite knowledge of the risk?

Heavy drinking among individuals with HIV: who drinks despite knowledge of the risk?
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DOI:
10.1080/09540121.2017.1382676
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发表时间:
2018-05
期刊:
影响因子:
1.7
通讯作者:
Hasin DS
Hasin DS
中科院分区:
医学4区
文献类型:
--
作者:
Elliott JC;Stohl M;Hasin DS

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大量饮酒可能会给艾滋病毒感染者带来医疗问题,尽管有医疗禁忌但仍饮酒是问题饮酒的一个指标。然而,尽管了解健康问题,但对于哪些艾滋病毒感染者饮酒却知之甚少。目前的研究使用了国家酒精和相关疾病流行病学调查 III (NESARC-III) 中的两个 HIV 感染者子样本:那些报告在其一生中至少饮酒过一次的人 (a) (n=205) 或 (b) 在过去一年 (n=166)。参与者报告了过去一年和一生中尽管存在健康问题和精神病理学症状但仍饮酒的情况,以及是否存在酗酒问题的家族史。患有吸毒障碍(调整优势比 [AOR] = 3.56–12.65)、重度抑郁症(AOR = 10.18–10.55)或有酗酒问题家族史(AOR=33.60–96.01)的个体尽管存在健康问题,但更有可能饮酒。焦虑和人格障碍并不能预测风险增加。尽管存在健康问题,但患有吸毒障碍或重度抑郁症的艾滋病毒感染者可能更有可能饮酒。有酗酒问题家族史的人也更有可能从事这种危险行为,尽管考虑到置信区间较大,还需要进一步研究。未来的研究应该考虑如何最好地帮助这些高危人群避免与酒精相关的伤害。
Heavy alcohol use can cause medical problems for individuals with HIV, and drinking despite medical contraindications is an indicator of problem use. However, little is known about which individuals with HIV drink despite knowledge of health problems. The current study utilizes two subsamples of individuals with HIV from the National Epidemiologic Survey on Alcohol and Related Conditions-III (NESARC-III): those reporting at least one drink (a) in their lifetime (n=205) or (b) in the past year (n=166). Participants reported on drinking despite health problems and symptoms of psychopathology in the past year and in their lifetime, as well as the presence or absence of a family history of alcohol problems. Individuals with a drug use disorder (Adjusted Odds Ratios [AORs] = 3.56–12.65), major depressive disorder (AORs = 10.18–10.55), or a family history of alcohol problems (AORs=33.60–96.01) were more likely to drink despite health problems. Anxiety and personality disorders did not predict increased risk. Individuals with HIV who suffer from drug use disorders or major depressive disorder may be more likely to drink alcohol despite health problems. Individuals who have a family history of alcohol problems were also more likely to engage in this risky behavior, although further research is needed given large confidence intervals. Future research should consider how to best help these at-risk groups avoid alcohol-related harm.
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