Impact of Air Pollution and Weather on Dry Eye.

Impact of Air Pollution and Weather on Dry Eye.
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DOI:
10.3390/jcm9113740
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发表时间:
2020-11-20
影响因子:
3.9
通讯作者:
Galor A
Galor A
中科院分区:
医学2区
文献类型:
--
作者:
Mandell JT;Idarraga M;Kumar N;Galor A

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空气污染对人体健康有广泛的影响,涉及许多器官系统。眼表是研究空气污染对人类健康影响的一个很好的模型,因为它与环境不断接触,并且可以直接接触,便于疾病监测。空气污染物对眼表的影响通常表现为干眼(DE)症状和体征。在这篇综述中,我们将空气污染分解为颗粒物(有机和无机)和气态化合物,并总结了有关各种暴露对DE影响的文献。此外,我们还研究了天气(相对湿度,温度)对DE症状和体征的影响。为此,我们使用关键词进行了PubMed检索,以总结现有的关于空气污染和天气对DE影响的文献。虽然我们试图专注于特定暴露对DE特定方面的影响,但环境条件往往伴随着研究,因此,我们感兴趣的变量之间存在不可避免的相互作用。总体而言,我们发现空气污染和天气条件对DE症状和体征有不同的不利影响。我们讨论了这些发现和潜在的缓解策略,如空气净化器,空气加湿器,和植物,可以制定为在个人层面上的治疗,以解决环境贡献DE。
Air pollution has broad effects on human health involving many organ systems. The ocular surface is an excellent model with which to study the effects of air pollution on human health as it is in constant contact with the environment, and it is directly accessible, facilitating disease monitoring. Effects of air pollutants on the ocular surface typically manifest as dry eye (DE) symptoms and signs. In this review, we break down air pollution into particulate matter (organic and inorganic) and gaseous compounds and summarize the literature regarding effects of various exposures on DE. Additionally, we examine the effects of weather (relative humidity, temperature) on DE symptoms and signs. To do so, we conducted a PubMed search using key terms to summarize the existing literature on the effects of air pollution and weather on DE. While we tried to focus on the effect of specific exposures on specific aspects of DE, environmental conditions are often studied concomitantly, and thus, there are unavoidable interactions between our variables of interest. Overall, we found that air pollution and weather conditions have differential adverse effects on DE symptoms and signs. We discuss these findings and potential mitigation strategies, such as air purifiers, air humidifiers, and plants, that may be instituted as treatments at an individual level to address environmental contributors to DE.
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