Breastfeeding, maternal education and cognitive function: a prospective study in twins.

Breastfeeding, maternal education and cognitive function: a prospective study in twins.
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DOI:
10.1007/s10519-009-9293-9
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发表时间:
2009-11
期刊:
影响因子:
2.6
通讯作者:
Boomsma, D. I.
Boomsma, D. I.
中科院分区:
医学3区
文献类型:
--
作者:
Bartels, M.;van Beijsterveldt, C. E. M.;Boomsma, D. I.

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母乳喂养对认知能力的影响是在高学历妇女的后代进行检查,并与低或中等教育程度的妇女的影响进行比较。所有的后代包括12岁的单卵或双卵双胞胎,这使得研究母乳喂养对平均认知得分的影响以及母乳喂养对认知变异遗传率的调节作用成为可能。向6 569名儿童提供了关于母乳喂养和认知能力的信息。在婴儿出生后的头几年对母乳喂养状况进行前瞻性评估。母亲的教育程度与后代在认知能力标准化测试中的表现呈正相关。还观察到母乳喂养对认知的显著影响。对于母亲具有高、中、低教育水平的后代,效果相似。在认知能力的标准化测试(CITO测试;范围500-550;效应量= 0.936)中,受过高等教育的母亲母乳喂养的孩子比受教育程度低的母亲配方奶粉喂养的孩子平均高出7.6分。认知得分的个体差异主要是由加性遗传因素(80%)和母乳喂养不修改任何三个层次的母亲教育的遗传因素的影响。母亲受中等教育程度的儿童遗传力略低。
The effect of breastfeeding on cognitive abilities is examined in the offspring of highly educated women and compared to the effects in women with low or middle educational attainment. All offspring consisted of 12-year old mono- or dizygotic twins and this made it possible to study the effect of breastfeeding on mean cognition scores as well as the moderating effects of breastfeeding on the heritability of variation in cognition. Information on breastfeeding and cognitive ability was available for 6,569 children. Breastfeeding status was prospectively assessed in the first years after birth of the children. Maternal education is positively associated with performance on a standardized test for cognitive ability in offspring. A significant effect of breastfeeding on cognition was also observed. The effect was similar for offspring with mothers with a high, middle, and low educational level. Breast-fed children of highly educated mothers score on average 7.6 point higher on a standardized test of cognitive abilities (CITO test; range 500–550; effects size = .936) than formula-fed children of mothers with a low education. Individual differences in cognition scores are largely accounted for by additive genetic factors (80%) and breastfeeding does not modify the effect of genetic factors in any of the three strata of maternal education. Heritability was slightly lower in children with a mother with a middle-level education.
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影响因子: 2.5
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