Immune microenvironment profiles of tumor immune equilibrium and immune escape states of mouse sarcoma.
Immune microenvironment profiles of tumor immune equilibrium and immune escape states of mouse sarcoma.
复制标题
小鼠肉瘤肿瘤免疫平衡和免疫逃逸状态的免疫微环境特征。
DOI：
10.1016/j.canlet.2013.07.038
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发表时间：
2013-10
期刊：
影响因子：
9.7
通讯作者：
Rongxin Zhang
中科院分区：
文献类型：
--
作者：
Xi Wu, et al;Rongxin Zhang
Cancer immunoediting consists of three distinct phases: elimination, equilibrium and escape. Here, for the first time, we investigated the immune microenvironment profiles of tumor immune equilibrium and immune escape states in 3′-methylcholanthrene-induced murine sarcoma model. Our study indicates the relative balance of monocytic MDSCs and antitumor immunity cells (especially CTLs, NK cells and γδT cells) may involve in maintaining tumor cells in a state of immune-mediated dormancy. In addition, high percentages of Treg cells and PMN-MDSCs are associated with the tumor immune escape state – mice with progressing sarcomas. In summary, the relative balance of immune effector cells and suppressive populations in the tumor microenvironment may involve in determining the fate of tumors.
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影响因子：
11.2
作者：
Ozao-Choy J;Ma G;Kao J;Wang GX;Meseck M;Sung M;Schwartz M;Divino CM;Pan PY;Chen SH
通讯作者：
Chen SH
影响因子：
14.5
作者：
J. Uhr;R. Marches
通讯作者：
J. Uhr;R. Marches
影响因子：
8.8
作者：
Mizukami, Y.;Kono, K.;Kawaguchi, Y.;Akaike, H.;Kamimura, K.;Sugai, H.;Fujii, H.
通讯作者：
Fujii, H.
影响因子：
--
作者：
H. Qiu;Wu Xiao-Jun;Zhou Zhi-wei;Chen Gong;Wang Guo-qiang;Zhang Li-yi;Li Yuan-fang;Keshari Rajiv-Prasad
通讯作者：
H. Qiu;Wu Xiao-Jun;Zhou Zhi-wei;Chen Gong;Wang Guo-qiang;Zhang Li-yi;Li Yuan-fang;Keshari Rajiv-Prasad
影响因子：
4.4
作者：
Almand, B;Clark, JI;Gabrilovich, DI
通讯作者：
Gabrilovich, DI