Effects of high-dose B vitamin complex with vitamin C and minerals on subjective mood and performance in healthy males.
Effects of high-dose B vitamin complex with vitamin C and minerals on subjective mood and performance in healthy males.
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DOI：
10.1007/s00213-010-1870-3
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发表时间：
2010-07
影响因子：
3.4
通讯作者：
Haskell, Crystal F.
中科院分区：
文献类型：
--
作者：
Kennedy, David O.;Veasey, Rachel;Watson, Anthony;Dodd, Fiona;Jones, Emma;Maggini, Silvia;Haskell, Crystal F.
相当大比例的普通民众报告说，他们在饮食中补充一种或多种维生素或矿物质，这样做的常见原因是为了对抗压力和疲劳，改善精神功能。很少有研究评估补充维生素/矿物质与非老年人健康人群心理功能之间的关系。目前的随机、安慰剂对照、双盲、平行组试验评估了高剂量b族复合维生素和矿物质补充剂（Berocca®）对215名年龄在30至55岁的全职男性的认知和情绪影响。参与者在33天治疗期之前和最后一天到实验室完成情绪状态概况（POMS）、感知压力量表（PSS）和一般健康问卷（GHQ-12）。用60分钟认知需求电池评估认知表现和任务相关的情绪/疲劳调节。在最后一天，参与者还完成了40分钟的Stroop任务，同时进行了倾斜跑步机行走，并评估了随后的执行功能。维生素/矿物质的补充导致PSS， GHQ-12和POMS的“活力”分量表的评分显著提高。维生素/矿物质组在系列3减法任务中表现更好，在认知需求电池完成前后，他们都认为自己不那么“精神疲劳”。一般人群的健康成员可以通过直接膳食补充来增加维生素/矿物质的水平。具体来说，补充叶酸可以改善压力、心理健康和活力的评分，并在紧张的心理处理过程中改善认知表现。
A significant proportion of the general population report supplementing their diet with one or more vitamins or minerals, with common reasons for doing so being to combat stress and fatigue and to improve mental functioning. Few studies have assessed the relationship between supplementation with vitamins/minerals and psychological functioning in healthy cohorts of non-elderly adults. The present randomised, placebo-controlled, double–blind, parallel groups trial assessed the cognitive and mood effects of a high-dose B-complex vitamin and mineral supplement (Berocca®) in 215 males aged 30 to 55 years, who were in full-time employment. Participants attended the laboratory prior to and on the last day of a 33-day treatment period where they completed the Profile of Mood States (POMS), Perceived Stress Scale (PSS) and General Health Questionnaire (GHQ-12). Cognitive performance and task-related modulation of mood/fatigue were assessed with the 60 min cognitive demand battery. On the final day, participants also completed the Stroop task for 40 min whilst engaged in inclined treadmill walking and subsequent executive function was assessed. Vitamin/mineral supplementation led to significant improvements in ratings on the PSS, GHQ-12 and the ‘vigour’ subscale of the POMS. The vitamin/mineral group also performed better on the Serial 3s subtractions task and rated themselves as less ‘mentally tired’ both pre- and post-completion of the cognitive demand battery. Healthy members of the general population may benefit from augmented levels of vitamins/minerals via direct dietary supplementation. Specifically, supplementation led to improved ratings of stress, mental health and vigour and improved cognitive performance during intense mental processing.
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影响因子：
5
作者：
COHEN, S;KAMARCK, T;MERMELSTEIN, R
通讯作者：
MERMELSTEIN, R
影响因子：
7.1
作者：
Eilander, Ans;Gera, Tarun;Osendarp, Saskia J. M.
通讯作者：
Osendarp, Saskia J. M.
影响因子：
3.3
作者：
Elias, Merrill F.;Robbins, Michael A.;Bates, Christopher J.
通讯作者：
Bates, Christopher J.
影响因子：
168.9
作者：
Durga, Jane;van Boxtel, Martin P. J.;Verhoef, Petra
通讯作者：
Verhoef, Petra
影响因子：
4.2
作者：
Durga, J;van Boxtel, MPJ;Verhoef, P
通讯作者：
Verhoef, P