Processing and memory for emotional and neutral material in amyotrophic lateral sclerosis.

Processing and memory for emotional and neutral material in amyotrophic lateral sclerosis.
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DOI:
10.3109/17482968.2012.708936
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发表时间:
2012-10
期刊:
Amyotrophic lateral sclerosis : official publication of the World Federation of Neurology Research Group on Motor Neuron Diseases
影响因子:
--
通讯作者:
Goldstein LH
Goldstein LH
中科院分区:
其他
文献类型:
--
作者:
Cuddy M;Papps BJ;Thambisetty M;Leigh PN;Goldstein LH

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一些研究报告了ALS患者(ALS)情绪记忆和处理的变化。在这项研究中,我们试图分析情绪处理和记忆的差异,并调查情绪记忆和自我报告的抑郁症之间的关系。对19名ALS患者和19名健康对照者的情绪处理、情绪记忆、言语记忆和抑郁进行了评估。尽管在情绪记忆的测量上,患者和对照组没有显著差异,但一个亚组的患者在情绪识别任务上表现不佳。在情绪加工方面,MCAALS对积极词的情绪效价评分显著高于消极词。在控制组中,情感词的高评分与更好的回忆有关,但在实验组中则不然。自我报告的抑郁症和情绪处理或记忆变量在两组中均不相关。总之,这项小型研究的结果表明,一个亚组的MANAALS可能表现出减弱的“情绪增强”,尽管在目前的样本中,这可能反映了一般的记忆障碍,而不是情绪记忆的具体变化。尽管如此,不同的模式处理的情绪突出的材料,MATERIALS可能有护理和管理相关的影响。
Several studies have reported changes in emotional memory and processing in people with ALS (pwALS). In this study, we sought to analyse differences in emotional processing and memory between pwALS and healthy controls and to investigate the relationship between emotional memory and self-reported depression. Nineteen pwALS and 19 healthy controls were assessed on measures of emotional processing, emotional memory, verbal memory and depression. Although pwALS and controls did not differ significantly on measures of emotional memory, a subgroup of patients performed poorly on an emotional recognition task. With regard to emotional processing, pwALS gave significantly stronger ratings of emotional valence to positive words than to negative words. Higher ratings of emotional words were associated with better recall in controls but not pwALS. Self-reported depression and emotional processing or memory variables were not associated in either group. In conclusion, the results from this small study suggest that a subgroup of pwALS may show weakened ‘emotional enhancement’, although in the current sample this may reflect general memory impairment rather than specific changes in emotional memory. Nonetheless, different patterns of processing of emotionally-salient material by pwALS may have care and management-related implications.
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