Functional cortical hubs in the eyes-closed resting human brain from an electrophysiological perspective using magnetoencephalography.

Functional cortical hubs in the eyes-closed resting human brain from an electrophysiological perspective using magnetoencephalography.
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DOI:
10.1371/journal.pone.0068192
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发表时间:
2013
期刊:
影响因子:
3.7
通讯作者:
Chung CK
Chung CK
中科院分区:
综合性期刊3区
文献类型:
--
作者:
Jin SH;Jeong W;Seol J;Kwon J;Chung CK

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目前尚不清楚特定的大脑区域是否在闭眼(EC)休息状态下充当枢纽,这是一种不受任何被动或主动任务约束的状态。在这里,我们使用电生理脑磁图(MEG)信号来研究88名参与者的功能皮层枢纽。我们发现了几个多光谱皮层中枢。虽然皮质枢纽略有不同,不同的应用措施和频带,最一致的枢纽中观察到内侧和后扣带皮层,左背外侧上级额叶皮层,和左极的中颞叶皮层。枢纽的特点是连接节点集成EC静息态功能网络。γ带中的中心更可能包括中线结构。我们的研究结果证实了EC静息态功能网络的基础上MEG的多光谱皮层核心的存在,并意味着在静息脑中存在优化的功能网络。
It is not clear whether specific brain areas act as hubs in the eyes-closed (EC) resting state, which is an unconstrained state free from any passive or active tasks. Here, we used electrophysiological magnetoencephalography (MEG) signals to study functional cortical hubs in 88 participants. We identified several multispectral cortical hubs. Although cortical hubs vary slightly with different applied measures and frequency bands, the most consistent hubs were observed in the medial and posterior cingulate cortex, the left dorsolateral superior frontal cortex, and the left pole of the middle temporal cortex. Hubs were characterized as connector nodes integrating EC resting state functional networks. Hubs in the gamma band were more likely to include midline structures. Our results confirm the existence of multispectral cortical cores in EC resting state functional networks based on MEG and imply the existence of optimized functional networks in the resting brain.
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