Prenatal exposure to tobacco and cannabis, early cannabis initiation, and daily dual use of combustible cigarettes and cannabis during young adulthood.
Prenatal exposure to tobacco and cannabis, early cannabis initiation, and daily dual use of combustible cigarettes and cannabis during young adulthood.
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DOI：
10.1016/j.addbeh.2021.106820
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发表时间：
2021-05
影响因子：
4.4
通讯作者：
Day NL
中科院分区：
文献类型：
--
作者：
De Genna NM;Goldschmidt L;Richardson GA;Cornelius MD;Day NL
每天使用可燃香烟在大麻使用者中很常见，香烟和大麻的双重使用与有害后果有关。这项研究通过检查产前和青春期阶段的数据来解决文献中的空白，这是一项预测成人日常两用的前瞻性纵向研究。年轻的成年子女(男性=22.8岁，53%女性)来自产前队列，报告使用可燃香烟和大麻(N=500，58%黑人，42%白人)。使用研究中妊娠期和青春期的变量，包括产前吸烟、酒精和大麻暴露；开始吸烟和大麻的年龄；以及青春期学习/记忆、冲动和行为问题，对日常双重使用的路径进行建模。产前大麻和烟草的使用与成人每日大麻和烟草的双重使用没有直接联系。然而，结构方程模型揭示了从产前吸烟和大麻暴露到成人日常香烟和大麻双重使用的三条重要间接途径，即通过早期开始吸烟、早期开始吸食大麻和青少年行为问题。这项研究确定了从产前大麻和烟草暴露到成人日常双重使用的途径，此外还澄清了可能是途径的一部分的青少年结果。在大麻使用日益被接受和娱乐使用日益合法化的环境下，这些调查结果是一个警告，即早期接触大麻可能在形成烟草和大麻的长期双重使用方面发挥重要作用。
Daily combustible cigarette use is common among cannabis users, and dual use of cigarettes and cannabis is associated with detrimental outcomes. This study addresses gaps in the literature by examining data from the prenatal and adolescent phases of a prospective, longitudinal study to predict adult daily dual use. Young adult offspring (M age = 22.8 years, 53% female) from a prenatal cohort reported on combustible cigarette, and cannabis use (N = 500, 58% Black, 42% White). Pathways to daily dual use were modeled using variables from the gestational and adolescent phases of the study including prenatal tobacco, alcohol, and cannabis exposures; ages at initiation of cigarettes and cannabis; and adolescent learning/memory, impulsivity, and behavior problems. Prenatal cannabis and tobacco use were not directly linked to adult daily dual use of cannabis and tobacco. However, structural equation modeling revealed three significant indirect pathways from prenatal cigarette and cannabis exposures to adult daily dual use of cigarettes and cannabis via early cigarette initiation, early cannabis initiation, and adolescent behavior problems. This study identified pathways from prenatal cannabis and tobacco exposure to adult daily dual use, in addition to clarifying adolescent outcomes that may be part of the pathways. In a climate of growing acceptance of cannabis use and increasing legalization of recreational use, these findings serve as a warning that early exposure to cannabis may have an important role in shaping long-term dual use of tobacco and cannabis.
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影响因子：
4.2
作者：
CHASSIN, L;PRESSON, CC;EDWARDS, DA
通讯作者：
EDWARDS, DA
影响因子：
4.4
作者：
Montgomery, LaTrice
通讯作者：
Montgomery, LaTrice
影响因子：
2.3
作者：
Cornelius MD;Goldschmidt L;De Genna NM;Larkby C
通讯作者：
Larkby C
影响因子：
4.4
作者：
Chen, Chuan-Yu;Storr, Carla L.;Anthony, James C.
通讯作者：
Anthony, James C.
DOI：
10.1016/j.drugpo.2020.102754
发表时间：
2020-04-16
期刊：
The International journal on drug policy
影响因子：
--
作者：
Gravely S;Driezen P;Smith DM;Borland R;Lindblom EN;Hammond D;McNeill A;Hyland A;Cummings KM;Chan G;Thompson ME;Boudreau C;Martin N;Ouimet J;Loewen R;Quah ACK;Goniewicz ML;Thrasher JF;Fong GT
通讯作者：
Fong GT