The impact of the Uighur medicine abnormal savda munziq on antitumor and antioxidant activity in a S180 and Ehrlich ascites carcinoma mouse tumor model.
The impact of the Uighur medicine abnormal savda munziq on antitumor and antioxidant activity in a S180 and Ehrlich ascites carcinoma mouse tumor model.
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在S180和Ehrlich腹水癌小鼠肿瘤模型中，Uighur医学异常SAVDA MUNZIQ对抗肿瘤和抗氧化活性的影响。
DOI：
10.4103/0973-1296.96568
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发表时间：
2012-04
影响因子：
0.7
通讯作者：
Upur H
中科院分区：
文献类型：
--
作者：
Aikemu A;Yusup A;Umar A;Berké B;Moore N;Upur H
以S180和埃利希腹水癌小鼠为模型，研究维药异常黑胆质成熟剂（ASMq）的抗肿瘤和抗氧化作用。测定小鼠血清超氧化物歧化酶（SOD）、丙二醛（MDA）和谷胱甘肽-过氧化氢酶（GSH-PX）的含量，并进行耐缺氧试验。并对它们的攀爬能力进行了分析。结果表明，ASMq处理后，血清SOD和GSH-PX水平升高，而MDA水平降低。此外，ASMq-治疗提高了小鼠在缺氧条件下的存活时间，并提高了小鼠的攀爬能力。结果表明ASMq具有明显的抗肿瘤和抗氧化作用。
This study was designed to study the antitumor and antioxidant activity of Uighur medicine abnormal savda munziq (ASMq) in the S180 and Ehrlich ascites carcinoma mice tumor model. The serum levels of superoxide dismutase (SOD), malonaldehyde (MDA), and glutathione-catalase (GSH-PX) were analyzed, and the mice were also subjected to a hypoxia tolerance test. Their climbing ability was also analyzed. The findings of the study revealed that ASMq-treatment leads to an increase in blood serum SOD and GSH-PX levels but a decrease in blood serum MDA levels. Moreover, ASMq-treatment enhanced the survival time of mice maintained under hypoxic conditions and improved their mice climbing ability. The results of this study indicate that ASMq has obvious antitumor and antioxidative effects.
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DOI：
10.1097/00004647-200204000-00003
发表时间：
2002-04-01
影响因子：
6.3
作者：
Bernaudin, M;Nedelec, AS;Schumann-Bard, P
通讯作者：
Schumann-Bard, P
影响因子：
3.6
作者：
Kuloglu, M;Ustundag, B;Cinkilinc, N
通讯作者：
Cinkilinc, N
影响因子：
5
作者：
Inal, ME;Kanbak, G;Sunal, E
通讯作者：
Sunal, E
影响因子：
8.3
作者：
Prass, K;Scharff, A;Meisel, A
通讯作者：
Meisel, A
影响因子：
4.3
作者：
Ku, Sae-Kwang;Seo, Bu-Il;Roh, Seong-Soo
通讯作者：
Roh, Seong-Soo