Mycosporine-Like Amino Acids: Potential Health and Beauty Ingredients.

Mycosporine-Like Amino Acids: Potential Health and Beauty Ingredients.
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DOI:
10.3390/md15100326
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发表时间:
2017-10-21
期刊:
影响因子:
5.4
通讯作者:
Bialczyk J
Bialczyk J
中科院分区:
医学2区
文献类型:
--
作者:
Chrapusta E;Kaminski A;Duchnik K;Bober B;Adamski M;Bialczyk J

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人类皮肤经常暴露在破坏性紫外线辐射(UVR)下,导致许多急慢性疾病。为了减少紫外线导致的皮肤损伤的风险,人们使用含有防晒霜的化妆品形式的额外外部保护。如今,由于一些化学滤光剂的使用引起了很大的争议,研究的重点是探索新颖、完全安全和高效的天然紫外线吸收化合物,作为防晒产品的活性成分。一种有前景的替代方案是应用多功能霉菌素样氨基酸(MAAs),它可以有效地与商业上可用的过滤器竞争。在这里,我们概述了这些化合物的完整特征,并讨论了它们巨大的生物技术潜力,特别强调了它们作为防晒霜、细胞增殖激活剂、抗癌剂、抗光老化分子、皮肤更新刺激剂以及防紫外线生物材料的功能成分的用途。
Human skin is constantly exposed to damaging ultraviolet radiation (UVR), which induces a number of acute and chronic disorders. To reduce the risk of UV-induced skin injury, people apply an additional external protection in the form of cosmetic products containing sunscreens. Nowadays, because of the use of some chemical filters raises a lot of controversies, research focuses on exploring novel, fully safe and highly efficient natural UV-absorbing compounds that could be used as active ingredients in sun care products. A promising alternative is the application of multifunctional mycosporine-like amino acids (MAAs), which can effectively compete with commercially available filters. Here, we outline a complete characterization of these compounds and discuss their enormous biotechnological potential with special emphasis on their use as sunscreens, activators of cells proliferation, anti-cancer agents, anti-photoaging molecules, stimulators of skin renewal, and functional ingredients of UV-protective biomaterials.
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