Magnetic Resonance Imaging Criteria for Post-concussion Syndrome (PCS): A study of 127 PCS Patients.
Magnetic Resonance Imaging Criteria for Post-concussion Syndrome (PCS): A study of 127 PCS Patients.
复制标题
脑震荡后综合症 (PCS) 的磁共振成像标准：一项针对 127 名 PCS 患者的研究。
作者：
J. Panwar;C. Hsu;Charles Tator;D. Mikulis
本研究的目的是评估脑震荡后综合征（PCS）患者的大型前瞻性队列中常规MRI脑结构病变的频率。使用传统3 T MRI评估了127名前瞻性入组的PCS患者和29名对照组的非特异性白色高信号（WMH）和创伤性结构性病变，包括脑软化、萎缩、微出血、蛛网膜下腔出血和皮质铁质沉着症。所有PCS患者均根据运动组（CISG）共识声明中的脑震荡进行了一次或多次脑震荡的临床诊断。排除了既往头部CT和MRI确认的颅内出血患者。分析PCS组和对照组之间的差异。PCS组有4例（3.1%）患者有阳性发现，其中2例患者有微血管病变，另2例患者有脑软化。对照组中不存在这些病变，但两组之间无统计学差异（微出血P = 0.5，脑软化P = 0.5）。在PCS组中，28例患者（22%）患有WMH（15.7%有1-10处病变，6.3%有> 10处病变），这些结果与年龄匹配的对照组（20.6%，均≥ 1-10处病变）无差异，P =0.9。WMH的位置显示PCS组和对照组之间的前皮质WMH的数量无显著差异（P = 0.5）。在这项研究中，PCS的结构性病变很少见，这些发现的存在表明了一种更严重的创伤性脑损伤。我们的数据支持MRI在PCS诊断中的作用，排除了萎缩、脑软化和各种形式的颅内出血。WMH的存在，无论数量多少，都不是一种排除。这是首次描述PCS的MRI标准。关键词-神经影像学标准;脑震荡后综合征;磁共振成像;脑血管造影;白色高信号。
The purpose of this study was to assess the frequency of structural lesions on conventional MRI of the brain in a large prospective cohort of post-concussion syndrome (PCS) patients. Conventional 3T MRI was used to evaluate 127 prospectively enrolled PCS patients and 29 controls for non-specific white matter hyperintensities (WMH) and traumatic structural lesions including encephalomalacia, atrophy, microhemorrhage, subarachnoid hemorrhage and cortical siderosis. All PCS patients had the clinical diagnosis of one or more concussions based on the Concussion in Sport Group (CISG) consensus statements. Patients with recognized intracranial hemorrhage on prior head CT and MRI were excluded. The differences between the PCS and control groups were analyzed. Four patients in the PCS group (3.1%) had positive findings which included microhemorrhages in two patients and encephalomalacia in another two patients. None of these lesions was present in the control group but there was no statistical difference between the two groups (P = 0.5 for microhemorrhage and P = 0.5 for encephalomalacia). In the PCS group, 28 patients (22%) had WMH (15.7% had 1-10 lesions and 6.3% had > 10 lesions), and these results did not differ from the age-matched control (20.6%, all with =1-10 lesions), P =0.9. The location of the WMH showed no significant difference in the number of juxtacortical WMH between the PCS and control groups (P = 0.5). Structural lesions were rare in PCS in this study and the presence of such findings suggests a more severe form of traumatic brain injury. Our data support the role for MRI in the diagnosis of PCS by exclusion of atrophy, encephalomalacia and all forms of intracranial hemorrhage. The presence of WMH irrespective of number is not an exclusion. This is the first description of the MRI criteria for PCS. Keywords-Neuroimaging Criteria; post-concussion syndrome; magnetic resonance imaging; hemorrhages; white matter hyperintensities.
影响因子：
4.2
作者：
Koerte, Inga K.;Lin, Alexander P.;Shenton, Martha E.
通讯作者：
Shenton, Martha E.
影响因子：
2.5
作者：
Trifan, Gabriela;Gattu, Ramtilak;Benson, Randall R.
通讯作者：
Benson, Randall R.
在慢性创伤性脑损伤的兵役成员中成像脑微诊。
影响因子：
19.7
作者：
Liu W;Soderlund K;Senseney JS;Joy D;Yeh PH;Ollinger J;Sham EB;Liu T;Wang Y;Oakes TR;Riedy G
通讯作者：
Riedy G