Flow evaporimeter to assess evaporative resistance of human tear-film lipid layer

Flow evaporimeter to assess evaporative resistance of human tear-film lipid layer
复制标题

流动蒸发仪评估人体泪膜脂质层的蒸发阻力

DOI:
--
复制
发表时间:
2014
期刊:
影响因子:
--
通讯作者:
C. Radke
C. Radke
中科院分区:
--
文献类型:
--
作者:
Cheng;C. Cerretani;Yuzhang Li;S. Bowers;S. Shahsavarani;M. Lin;C. Radke

文献摘要

参考文献

被引文献

相似文献

研制了一种新型体内流蒸发仪,用于测量人体眼泪蒸发速率。流动蒸发器依赖于一个明确的流场,以已知的和可调的流量和相对湿度,并定量再现蒸发率为纯水。蒸发器数据的传质分析首次阐明了人体泪膜脂质层(TFLL)的阻力,以尽量减少对环境的眼泪损失。一项针对人体受试者的初步研究验证了流动蒸发器在体内获得泪膜蒸发速率的可行性。TFLL对泪液蒸发的阻力是特定主题的。我们的流量蒸发仪为干眼相关疾病的临床评估提供了一种准确、安全、方便的诊断工具。
A novel in vivo flow evaporimeter is developed to measure human tear-evaporation rates. The flow evaporimeter relies on a well-defined flow field to the eye with known and adjustable flow rates and relative humidities, and quantitatively reproduces evaporation rates for pure water. Mass-transfer analysis of the evaporimeter data elucidates, for the first time, the resistance of the human tear-film lipid layer (TFLL) toward minimizing tear loss to the environment. A pilot study on human subjects validates the feasibility of the flow evaporimeter to obtain the tear-film evaporation rates in vivo. Resistance of the TFLL against tear evaporation is found subject specific. Our flow evaporimeter offers an accurate, safe, and convenient diagnostic tool for clinical evaluation of dry-eye-related maladies.
DOI: 10.1167/iovs.10-6997c
发表时间: 2011-03-01
影响因子: 4.4
作者:
Knop, Erich;Knop, Nadja;Sullivan, David A.
通讯作者: Sullivan, David A.
蒸发对水性泪液损失的影响。
DOI: --
发表时间: 2006
期刊: Transactions of the American Ophthalmological Society
影响因子: --
作者:
McCulley,JamesP;Uchiyama,Eduardo;Aronowicz,JoelD;Butovich,IgorA
通讯作者: Butovich,IgorA
推测的分泌不足/蒸发过度的 KCS:泪液特征。
DOI: --
发表时间: 2003
期刊: Transactions of the American Ophthalmological Society.
影响因子: --
作者:
McCulley,JamesP;Shine,WardE;Aronowicz,Joel;Oral,Deniz;Vargas,Jose
通讯作者: Vargas,Jose
DOI: 10.1167/iovs.09-4744
发表时间: 2010-08-01
影响因子: 4.4
作者:
Hirata, Harumitsu;Meng, Ian D.
通讯作者: Meng, Ian D.
DOI: 10.1167/iovs.10-6997a
发表时间: 2011-03-01
影响因子: 4.4
作者:
Nichols, Kelly K.;Foulks, Gary N.;Sullivan, David A.
通讯作者: Sullivan, David A.