Severe mental illness and ophthalmic health: A linked administrative data study.
Severe mental illness and ophthalmic health: A linked administrative data study.
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DOI：
10.1371/journal.pone.0286860
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发表时间：
2023
期刊：
影响因子：
3.7
通讯作者：
中科院分区：
文献类型：
--
作者：
虽然有证据表明眼睛作为中枢神经系统的窗口具有潜在的益处，但关于严重精神疾病（SMI）和眼睛健康的研究却很少。我们研究了SMI与一系列眼科健康结果的相关性，以及是否有任何关系会因年龄而改变。我们使用来自全科医生（GP）、医院和眼科记录的关联管理数据，检查2015年1月至2019年11月期间北方爱尔兰（NI）医院人群（N = 798，564）接受的任何健康和社会护理（HSC）眼科检查;以及（基于视力检查记录的合格性）任何青光眼、任何糖尿病和任何失明。与非重度精神障碍患者相比，重度精神障碍患者视力检查、糖尿病和失明的患病率更高。在完全校正的logistic回归模型中，视力检查和糖尿病的可能性较高（OR = 1.71：95%CI分别为1.63，1.79和OR = 1.29：1.19，1.40）;青光眼的可能性较低（OR = 0.69：0.53，0.90）。有证据表明，在患有重度精神障碍的人群中，年龄较大的人群进行视力检查的可能性较低。我们的研究提供了与SMI相关的眼科健康不平等的新证据。虽然这项研究与其NI背景直接相关，但我们认为它可以推广到更广泛的英国健康问题。我们强调需要更多的这类研究，使用大型的电子管理数据库，以进一步了解与SMI和不良的眼睛健康相关的健康不平等，以及一般的健康结果。
While evidence has emerged highlighting the potential benefits of the eye as a window to the central nervous system, research on severe mental illness (SMI) and eye health is rare. We examine the association of SMI with a range of ophthalmic health outcomes, and whether any relationship is modified by age. We used linked administrative data from general practitioner (GP), hospital and ophthalmic records to examine receipt of any Health and Social Care (HSC) eye-test; and (based on eligibility recorded for a sight test) any glaucoma, any diabetes, and any blindness among the Northern Ireland (NI) hospital population between January 2015 and November 2019 (N = 798,564). When compared with non-SMI patients, those with SMI recorded a higher prevalence of having had a sight test, diabetes, and blindness. In fully adjusted logistic regression models, higher likelihood of an eye-test and diabetes (OR = 1.71: 95%CI = 1.63, 1.79 and OR = 1.29: 1.19, 1.40 respectively); and lower likelihood of glaucoma remained (OR = 0.69: 0.53, 0.90). Amongst persons with SMI there was evidence that the likelihood of having had an eye-test was lower in the older age-groups. Our study provides new evidence on ophthalmic health inequalities associated with SMI. While the study has immediate relevance to its NI context, we believe it is generalizable to wider UK health concerns. We emphasize the need for more research of this type, using large linkable electronic administrative databases to further our understanding of both health inequalities associated with SMI and poor eye health, and health outcomes in general.
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