ClueGO: a Cytoscape plug-in to decipher functionally grouped gene ontology and pathway annotation networks.

ClueGO: a Cytoscape plug-in to decipher functionally grouped gene ontology and pathway annotation networks.
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DOI:
10.1093/bioinformatics/btp101
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发表时间:
2009-04-15
期刊:
Bioinformatics (Oxford, England)
影响因子:
--
通讯作者:
Galon J
Galon J
中科院分区:
其他
文献类型:
--
作者:
Bindea G;Mlecnik B;Hackl H;Charoentong P;Tosolini M;Kirilovsky A;Fridman WH;Pagès F;Trajanoski Z;Galon J

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Summary: We have developed ClueGO, an easy to use Cytoscape plug-in that strongly improves biological interpretation of large lists of genes. ClueGO integrates Gene Ontology (GO) terms as well as KEGG/BioCarta pathways and creates a functionally organized GO/pathway term network. It can analyze one or compare two lists of genes and comprehensively visualizes functionally grouped terms. A one-click update option allows ClueGO to automatically download the most recent GO/KEGG release at any time. ClueGO provides an intuitive representation of the analysis results and can be optionally used in conjunction with the GOlorize plug-in. Availability: http://www.ici.upmc.fr/cluego/cluegoDownload.shtml Contact: jerome.galon@crc.jussieu.fr Supplementary information: Supplementary data are available at Bioinformatics online.
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