Life Span Studies of ADHD-Conceptual Challenges and Predictors of Persistence and Outcome.

Life Span Studies of ADHD-Conceptual Challenges and Predictors of Persistence and Outcome.
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DOI:
10.1007/s11920-016-0750-x
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发表时间:
2016-12
影响因子:
6.7
通讯作者:
Rohde LA
Rohde LA
中科院分区:
医学2区
文献类型:
--
作者:
Caye A;Swanson J;Thapar A;Sibley M;Arseneault L;Hechtman L;Arnold LE;Niclasen J;Moffitt T;Rohde LA

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有一个新的兴趣,更好地概念化的轨迹注意力缺陷/多动障碍(ADHD)从童年到成年,驱动的长期损害和潜在的持久性超越童年和青春期的认识增加。根据目前纵向研究的证据,本综述讨论了以下与ADHD病程相关的主要问题:(1)与ADHD持续性测量相关的概念和方法学问题,(2)从儿童到成年的持续率及其预测因素的估计,(3)儿童ADHD的长期负面结果及其早期预测因素,以及(4)最近提出的新的成人发作ADHD。文献中对持续性的估计差异很大,诊断标准、样本特征和信息来源是解释研究差异性的最重要因素。有证据表明,ADHD的严重程度,共病的行为障碍和重度抑郁症,以及ADHD的治疗是ADHD从童年到成年的持续性的主要预测因素。儿童期共病行为障碍和ADHD严重程度是ADHD儿童成年期不良结局的最重要预测因素。最近的三项人口研究表明,存在一个显着比例的个人谁报告的ADHD症状和损害的发病后,童年。最后,我们强调了需要改进的领域,以增加我们对ADHD的理解。
There is a renewed interest in better conceptualizing trajectories of attention-deficit/hyperactivity disorder (ADHD) from childhood to adulthood, driven by an increased recognition of long-term impairment and potential persistence beyond childhood and adolescence. This review addresses the following major issues relevant to the course of ADHD in light of current evidence from longitudinal studies: (1) conceptual and methodological issues related to measurement of persistence of ADHD, (2) estimates of persistence rate from childhood to adulthood and its predictors, (3) long-term negative outcomes of childhood ADHD and their early predictors, and (4) the recently proposed new adult-onset ADHD. Estimates of persistence vary widely in the literature, and diagnostic criteria, sample characteristics, and information source are the most important factors explaining variability among studies. Evidence indicates that ADHD severity, comorbid conduct disorder and major depressive disorder, and treatment for ADHD are the main predictors of ADHD persistence from childhood to adulthood. Comorbid conduct disorder and ADHD severity in childhood are the most important predictors of adverse outcomes in adulthood among children with ADHD. Three recent population studies suggested the existence of a significant proportion of individuals who report onset of ADHD symptoms and impairments after childhood. Finally, we highlight areas for improvement to increase our understanding of ADHD across the life span.
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