Touch spray mass spectrometry for in situ analysis of complex samples.

Touch spray mass spectrometry for in situ analysis of complex samples.
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触摸喷雾质谱法,用于对复杂样品的原位分析。

DOI:
10.1039/c4an00548a
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发表时间:
2014-06-07
期刊:
The Analyst
影响因子:
--
通讯作者:
Cooks RG
Cooks RG
中科院分区:
其他
文献类型:
--
作者:
Kerian KS;Jarmusch AK;Cooks RG

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接触喷雾是一种基于喷雾的原位环境电离方法,使用小探针(例如拨针)拾取样品,并施加电压和溶剂以引起场致液滴发射。从微量样品中提取的化合物被掺入喷雾的微滴中。性能测试包括组织的疾病状态、微生物鉴定和治疗药物定量。化学衍生与电离同时进行。
Touch spray, a spray-based ambient in-situ ionization method, uses a small probe, e.g. a teasing needle to pick up sample and the application of voltage and solvent to cause field-induced droplet emission. Compounds extracted from the microsample are incorporated into the sprayed micro droplets. Performance tests include disease state of tissue, microorganism identification, and therapeutic drug quantitation. Chemical derivatization is performed simultaneously with ionization.
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