Aging is not accompanied by sympathetic hyperresponsiveness to air-jet stress.
Aging is not accompanied by sympathetic hyperresponsiveness to air-jet stress.
复制标题
衰老并不伴随着交感神经对喷气压力的过度反应。
DOI：
10.1152/ajpheart.1996.271.2.h768
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发表时间：
1996
期刊：
影响因子：
--
通讯作者：
Kregel,KC
中科院分区：
文献类型：
--
作者：
Stauss,HM;Morgan,DA;Anderson,KE;Massett,MP;Kregel,KC
据推测，交感神经系统对急剧施加的压力的反应性随着年龄的增长而增加。我们研究了 9 只成熟（12 个月大）和 11 只衰老（24 个月大）Fischer 344 大鼠的自主神经和血流动力学调节。给大鼠安装动脉和静脉导管、肾动脉周围的流量探针以及同侧肾神经上的神经电极。大鼠从手术中恢复后，在对照条件下和 8 分钟连续喷气应用期间记录血压、心率、肾血流量和肾交感神经活动。离线计算肾阻力和血压的低频率（0.01-0.20 Hz）和中频（0.20-0.50 Hz）功率。空气喷射导致两组的血压、心率、肾阻力、肾神经活动和低频和中频范围的血压功率增加。与成熟大鼠相比，衰老大鼠的血压和低频血压功率增加较少，肾阻力和肾神经活动升高的持续时间较短。这些数据表明，交感神经对喷气压力的反应并没有随着年龄的增长而增强。
It has been postulated that sympathetic nervous system reactivity to acutely applied stress is increased with age. We investigated the autonomic and hemodynamic adjustments to air-jet stress in 9 mature (12-mo-old) and 11 senescent (24-mo-old) Fischer 344 rats. Rats were instrumented with arterial and venous catheters, flow probes around the renal artery, and nerve electrodes on the ipsilateral renal nerve. After the rats recovered from surgery, blood pressure, heart rate, renal blood flow, and renal sympathetic nerve activity were recorded during control conditions and during an 8-min continuous air-jet application. Renal resistance and the low (0.01-0.20 Hz)- and mid-frequency (0.20-0.50 Hz) power of blood pressure were computed off-line. The air jet induced an increase in blood pressure, heart rate, renal resistance, renal nerve activity, and blood pressure power in the low- and mid-frequency ranges in both groups. Blood pressure and low-frequency blood pressure power increased less, and the elevations in renal resistance and renal nerve activity were of shorter duration in senescent compared with mature rats. These data suggest that sympathetic responsiveness to air-jet stress is not enhanced with increasing age.
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正常血压和自发性高血压大鼠肾脏和内脏交感神经活动的记录。
影响因子：
6
作者：
P. Thoren;S.
通讯作者：
S.
影响因子：
8.3
作者：
ANDERSON, EA;WALLIN, BG;MARK, AL
通讯作者：
MARK, AL
DOI：
10.1093/geronj/37.2.130
发表时间：
1982-01-01
期刊：
JOURNALS OF GERONTOLOGY
影响因子：
--
作者：
YU, BP;MASORO, EJ;LYND, FT
通讯作者：
LYND, FT
动脉血压的低频功率是否反映了交感神经张力？
DOI：
--
发表时间：
1995
期刊：
Journal of the Autonomic Nervous System
影响因子：
--
作者：
H. Stauss;R. Mrowka;B. Nafz;A. Patzak;T. Unger;P. Persson
通讯作者：
P. Persson
临界高血压大鼠：研究环境诱发高血压机制的模型。
DOI：
10.1037//0278-6133.7.2.137
发表时间：
1988
期刊：
Health psychology : official journal of the Division of Health Psychology, American Psychological Association
影响因子：
--
作者：
Lawler,JE;Cox,RH;Sanders,BJ;Mitchell,VP
通讯作者：
Mitchell,VP