Anxiety symptoms and puberty interactively predict lower cingulum microstructure in preadolescent Latina girls.
Anxiety symptoms and puberty interactively predict lower cingulum microstructure in preadolescent Latina girls.
复制标题
DOI：
10.1038/s41598-022-24803-4
复制
发表时间：
2022-12-01
影响因子：
4.6
通讯作者：
Michalska, Kalina J.
中科院分区：
文献类型：
--
作者：
Glenn, Dana E.;Merenstein, Jenna L.;Bennett, Ilana J.;Michalska, Kalina J.
青春期前是焦虑的易感性增加的时期，特别是在拉丁裔女孩中。边缘和前额叶区域之间的白质束微结构减少(分数各向异性；FA)可能是焦虑症中调节障碍的基础。然而，关于焦虑和白质微结构之间的联系的发展研究是混合的，可能是由于与青春期的交互影响。在39名拉丁裔女孩(8-13岁)中，我们测试了青春期阶段是否缓和了父母和孩子报告的焦虑症状与扣带和钩状束FA之间的联系。父母而不是孩子报告的焦虑症状预示着扣带回FA较低，这种影响被青春期阶段缓和，因此这种联系只对青春期前的女孩显著。焦虑和青春期都不能预测钩束FA。这些发现表明，焦虑与女孩扣带白质微结构的破坏有关，这种关系在青春期经历了成熟的变化。
Preadolescence is a period of increased vulnerability for anxiety, especially among Latina girls. Reduced microstructure (fractional anisotropy; FA) of white matter tracts between limbic and prefrontal regions may underlie regulatory impairments in anxiety. However, developmental research on the association between anxiety and white matter microstructure is mixed, possibly due to interactive influences with puberty. In a sample of 39 Latina girls (8–13 years), we tested whether pubertal stage moderated the association between parent- and child-reported anxiety symptoms and FA in the cingulum and uncinate fasciculus. Parent- but not child-reported anxiety symptoms predicted lower cingulum FA, and this effect was moderated by pubertal stage, such that this association was only significant for prepubertal girls. Neither anxiety nor pubertal stage predicted uncinate fasciculus FA. These findings suggest that anxiety is associated with disruptions in girls’ cingulum white matter microstructure and that this relationship undergoes maturational changes during puberty.
登录
查看更多内容
影响因子：
--
作者：
Beesdo, Katja;Lau, Jennifer Y. F.;Guyer, Amanda E.;McClure-Tone, Erin B.;Monk, Christopher S.;Nelson, Eric E.;Fromm, Stephen J.;Goldwin, Michelle A.;Wittchen, Hans-Ulrich;Leibenluft, Ellen;Erns, Monique;Pine, Daniel S.
通讯作者：
Pine, Daniel S.
DOI：
10.1037/abn0000721
发表时间：
2022-01
期刊：
JOURNAL OF PSYCHOPATHOLOGY AND CLINICAL SCIENCE
影响因子：
--
作者：
Barendse, Marjolein E A;Byrne, Michelle L;Flournoy, John C;McNeilly, Elizabeth A;Guazzelli Williamson, Victoria;Barrett, Ann-Marie Y;Chavez, Samantha J;Shirtcliff, Elizabeth A;Allen, Nicholas B;Pfeifer, Jennifer H
通讯作者：
Pfeifer, Jennifer H
影响因子：
--
作者：
Beesdo, Katja;Bittner, Antje;Wittchen, Hans-Ulrich
通讯作者：
Wittchen, Hans-Ulrich
DOI：
10.1097/01.chi.0000046898.27264.a2
发表时间：
2003-08-01
影响因子：
13.3
作者：
Choudhury, MS;Pimentel, SS;Kendall, PC
通讯作者：
Kendall, PC
影响因子：
3.1
作者：
Andre, Quinn R.;Geeraert, Bryce L.;Lebel, Catherine
通讯作者：
Lebel, Catherine