Is Rheumatoid Arthritis Related to Coffee Consumption in Korea? A Nationwide Cross-Sectional Observational Study.

Is Rheumatoid Arthritis Related to Coffee Consumption in Korea? A Nationwide Cross-Sectional Observational Study.
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DOI:
10.3390/ijerph18157880
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发表时间:
2021-07-25
影响因子:
--
通讯作者:
Jung JH
Jung JH
中科院分区:
综合性期刊3区
文献类型:
--
作者:
Kim SG;Kang JW;Jeong SM;Song GG;Choi SJ;Jung JH

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韩国的咖啡消费量正在逐渐增加。因此,人们对咖啡消费与各种疾病之间的关系越来越感兴趣。有几个因素影响类风湿性关节炎(RA)的发展,咖啡消费可能与此有关。我们使用韩国国家健康和营养调查(2012-2016)的数据进行了一项全国性的横断面研究。共有12,465名合格参与者(4819名男性和7646名女性)被纳入研究。RA参与者被定义为那些被诊断并正在接受医生治疗的人。根据自我报告,每日咖啡消耗量分为无、<1杯、1-2杯、2-3杯和≥3杯。采用多变量logistic回归模型,计算了参与者患RA的几率与咖啡摄入量的比值比(OR)和95%置信区间(CI)。与不喝咖啡组相比,<1杯和1-2杯组的RA OR为2.99(95% CI 0.33-27.28)和2.63(95% CI 0.31-22.63),女性RA的OR分别为<1杯、1-2杯、2-3杯、和≥3杯组分别为0.62(95% CI 0.31-1.26)、0.67(95% CI 0.33-1.37)、1.08(95% CI 0.35-3.36)和1.43(95% CI 0.25-8.36)。因此,我们的研究得出的结论是,日常咖啡摄入量与韩国普通人群中RA的患病率无关。
Coffee consumption is gradually increasing in Korea. As a result, interest in the relationship between coffee consumption and various diseases is growing. Several factors affect the development of rheumatoid arthritis (RA), and coffee consumption may be related. We conducted a nationwide cross-sectional study using data from the Korea National Health and Nutrition Examination Survey (2012–2016). A total of 12,465 eligible participants (4819 men and 7646 women) were included in the study. Participants with RA were defined as those who were diagnosed and currently being treated by physicians. Daily coffee consumption amounts were categorized as none, <1 cup, 1–2 cups, 2–3 cups, and ≥3 cups a day based on a self-report. A multivariable logistic regression model was employed, and we calculated the odds ratios (ORs) and 95% confidence intervals (CIs) for the odds of participants having RA with respect to coffee consumption. Compared to the no-coffee group, the ORs for RA in the <1 cup and 1–2 cups groups were 2.99 (95% CI 0.33–27.28) and 2.63 (95% CI 0.31–22.63) in men, respectively, and the ORs for RA for women in the <1 cup, 1–2 cups, 2–3 cups, and ≥3 cups groups were 0.62 (95% CI 0.31–1.26), 0.67 (95% CI 0.33–1.37), 1.08 (95% CI 0.35–3.36), and 1.43 (95% CI 0.25–8.36), respectively. Our study concludes, therefore, that daily coffee consumption is not related to the prevalence of RA in the general Korean population.
DOI: 10.3390/jcm9103109
发表时间: 2020-09-26
影响因子: 3.9
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