Troubled Hearts: Association Between Heart Rate Variability and Depressive Symptoms in Healthy Children.
Troubled Hearts: Association Between Heart Rate Variability and Depressive Symptoms in Healthy Children.
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DOI：
10.1007/s10484-020-09488-7
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发表时间：
2020-12
影响因子：
3
通讯作者：
Stephen JM
中科院分区：
文献类型：
--
作者：
Gleichmann DC;Solis I;Janowich JR;Wang YP;Calhoun VD;Wilson TW;Stephen JM
心率变异性（HRV）捕捉连续心跳时间的变化，在抑郁和焦虑的个体中降低。本研究调查了没有临床公认的抑郁或焦虑症状的典型发育儿童是否表现出HRV与抑郁或焦虑症状之间的关系。9-14岁儿童（N=104）在闭眼休息和睁眼休息时提供3分钟的心脏信号。研究高频HRV、低频HRV、连续差异均方根（RMSSD）和pNN20与抑郁症状（NIH工具箱和儿童行为检查表）之间的关系。结果部分证实了我们的假设，在控制年龄、性别、社会地位和身体活动的情况下，pNN20与自我报告的孤独感抑郁测量呈正相关。这种关联在男性参与者中更为明显。然而，关于HRV测量与健康儿童抑郁症状之间的关系，文献中尚未达成共识。需要进一步的研究来可靠地解释影响HRV的变量，以确定某些HRV测量是否可以用作儿童抑郁风险的早期标记。
Heart rate variability (HRV) captures the change in timing of consecutive heart beats and is reduced in individuals with depression and anxiety. The present study investigated whether typically-developing children without clinically recognized signs of depression or anxiety showed a relationship between HRV and depressive or anxiety symptoms. Children aged 9-14 years (N=104) provided three minutes of cardiac signal during eyes closed rest and eyes open rest. The association between high frequency HRV, low frequency HRV, root mean square of the successive differences (RMSSD), and pNN20 versus depressive symptoms (NIH Toolbox and Child Behavior Checklist) was investigated. Results partially confirm our hypothesis, with pNN20 positively correlated with the self-reported depression measure of loneliness while controlling for age, sex, social status, and physical activity. The association was stronger in male participants. However, there is no consensus in the literature about which HRV measures are associated with depressive symptoms in healthy children. Additional studies are needed which reliably account for variables that influence HRV to establish whether certain HRV measures can be used as an early marker for depression risk in children.
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DOI：
10.1016/j.jpeds.2018.03.059
发表时间：
2018-08
期刊：
The Journal of pediatrics
影响因子：
--
作者：
Gross AC;Kaizer AM;Ryder JR;Fox CK;Rudser KD;Dengel DR;Kelly AS
通讯作者：
Kelly AS
影响因子：
3
作者：
Brown, Eoin Gavin;Creaven, Ann-Marie;Gallagher, Stephen
通讯作者：
Gallagher, Stephen
影响因子：
37.8
作者：
Elfassy, Tali;Swift, Samuel L.;Al Hazzouri, Adina Zeki
通讯作者：
Al Hazzouri, Adina Zeki
影响因子：
3.2
作者：
Bizik, Gustav;Bob, Petr;Zima, Tomas
通讯作者：
Zima, Tomas
影响因子：
6.6
作者：
Blood JD;Wu J;Chaplin TM;Hommer R;Vazquez L;Rutherford HJ;Mayes LC;Crowley MJ
通讯作者：
Crowley MJ