Commentary: Primary Transcripts of microRNAs Encode Regulatory Peptides.

Commentary: Primary Transcripts of microRNAs Encode Regulatory Peptides.
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评论:microRNA 的初级转录本编码调节肽

DOI:
10.3389/fpls.2016.01436
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发表时间:
2016
影响因子:
5.6
通讯作者:
Wang G
Wang G
中科院分区:
生物学2区
文献类型:
--
作者:
Lv S;Pan L;Wang G

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非编码RNA(ncRNA),包括微小RNA(miRNA)和长非编码RNA(lncRNA),被认为不能编码蛋白质(美世等人,2009; Rogers和Chen,2013; Patil等人,2014年)。衍生自初级miRNA(pri-miRNA)的miRNA通过抑制翻译或引导互补mRNA靶标的降解在转录后基因调控中发挥关键作用(Rogers和Chen,2013)。转录组和高通量测序分析揭示了各种生物体中的大量ncRNA(Kapusta和Feschotte,2014)。发现ncRNA涉及多种生物过程,包括植物生长和发育以及对环境胁迫的响应(美世等人,2009; Zhang等人,2013年; Kapusta和Feschotte,2014年)。
Noncoding RNAs (ncRNAs), including microRNAs (miRNAs) and long noncoding RNAs (lncRNAs), were assumed to be incapable of encoding proteins (Mercer et al., 2009; Rogers and Chen, 2013; Patil et al., 2014). miRNAs that derived from the primary miRNAs (pri-miRNAs) play crucial roles in post-transcriptional gene regulation by either repressing translation or guiding the degradation of complementary mRNA targets (Rogers and Chen, 2013). Transcriptome and high-throughput sequencing analyses have revealed a large number of ncRNAs in various organisms (Kapusta and Feschotte, 2014). It was found that ncRNAs were implicated in a variety of biological processes, including plant growth and development, and responses to environmental stresses (Mercer et al., 2009; Zhang et al., 2013; Kapusta and Feschotte, 2014).
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