Development of an Ocean Protein Portal for Interactive Discovery and Education.

Development of an Ocean Protein Portal for Interactive Discovery and Education.
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DOI:
10.1021/acs.jproteome.0c00382
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发表时间:
2021-01-01
影响因子:
4.4
通讯作者:
Kinkade DB
Kinkade DB
中科院分区:
生物学2区
文献类型:
--
作者:
Saito MA;Saunders JK;Chagnon M;Gaylord DA;Shepherd A;Held NA;Dupont C;Symmonds N;York A;Charron M;Kinkade DB

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Proteins are critical in catalyzing chemical reactions, forming key cellular structures, and in regulating cellular processes. Investigation of marine microbial proteins by metaproteomics methods enables the discovery of numerous aspects of microbial biogeochemical processes. However, these datasets present big data challenges as they often involve many samples collected across broad geospatial and temporal scales, resulting in thousands of protein identifications, abundances, and corresponding annotation information. The Ocean Protein Portal (OPP) was created to enable data sharing and discovery among multiple scientific domains and serve both research and education functions. The portal focuses on three use case questions: “Where is my protein of interest?”, “Who makes it?”, and “How much is there?” and provides profile and section visualizations, real-time taxonomic analysis, and links to metadata, sequence analysis, and other external resources to enable connections to be made between biogeochemical and proteomics datasets.
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