A Printed Organic Circuit System for Wearable Amperometric Electrochemical Sensors.

A Printed Organic Circuit System for Wearable Amperometric Electrochemical Sensors.
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DOI:
10.1038/s41598-018-24744-x
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发表时间:
2018-04-23
期刊:
影响因子:
4.6
通讯作者:
Tokito S
Tokito S
中科院分区:
综合性期刊3区
文献类型:
--
作者:
Shiwaku R;Matsui H;Nagamine K;Uematsu M;Mano T;Maruyama Y;Nomura A;Tsuchiya K;Hayasaka K;Takeda Y;Fukuda T;Kumaki D;Tokito S

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Wearable sensor device technologies, which enable continuous monitoring of biological information from the human body, are promising in the fields of sports, healthcare, and medical applications. Further thinness, light weight, flexibility and low-cost are significant requirements for making the devices attachable onto human tissues or clothes like a patch. Here we demonstrate a flexible and printed circuit system consisting of an enzyme-based amperometric sensor, feedback control and amplification circuits based on organic thin-film transistors. The feedback control and amplification circuits based on pseudo-CMOS inverters were successfuly integrated by printing methods on a plastic film. This simple system worked very well like a potentiostat for electrochemical measurements, and enabled the quantitative and real-time measurement of lactate concentration with high sensitivity of 1 V/mM and a short response time of a hundred seconds.
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