Predictors of cardiopulmonary hospitalization in chronic spinal cord injury.

Predictors of cardiopulmonary hospitalization in chronic spinal cord injury.
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DOI:
10.1016/j.apmr.2008.07.026
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发表时间:
2009-02
影响因子:
4.3
通讯作者:
Garshick E
Garshick E
中科院分区:
医学1区
文献类型:
--
作者:
Waddimba AC;Jain NB;Stolzmann K;Gagnon DR;Burgess JF Jr;Kazis LE;Garshick E

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我们调查了慢性脊髓损伤(SCI)退伍军人因循环和肺部疾病住院的纵向危险因素。循环系统和呼吸系统疾病是慢性脊髓损伤患者死亡的主要原因,但相关住院的危险因素尚未确定。前瞻性队列研究。退伍军人事务部(VA)波士顿医疗系统,波士顿,马萨诸塞州。来自VA-波士顿慢性脊髓损伤队列的309名退伍军人在脊髓损伤后1年完成了健康问卷并在研究开始时进行了肺活量测定。基线数据与退伍军人事务部国家患者护理数据库中1996-2003年的住院记录相关联。不适用。心肺住院的预测因素用多变量COX回归进行评估。在观察到的1478例入院病例中,143例是由于心肺疾病(77例循环系统疾病和66例呼吸系统疾病)。独立的预测因素是年龄较大(每年增加3%)、高血压以及体重指数最低的五分位数(22.4公斤/平方米)。预测的FEV1百分比越大,风险就越低。在调整了这些危险因素后,脊髓损伤程度和损伤的完整性没有统计学意义。慢性脊髓损伤患者的心肺住院风险与较大的年龄和医学因素有关,如果认识到这些因素,可能会导致减少未来住院的策略。
We investigated longitudinal risk factors of hospitalization for circulatory and pulmonary diseases among veterans with chronic spinal cord injury (SCI). Circulatory and respiratory system illnesses are leading causes of death in chronic SCI patients, yet risk factors for related hospitalizations have not been characterized. Prospective cohort study. Veterans Affairs (VA) Boston Healthcare System, Boston, Massachusetts. 309 veterans ≥ 1 year post-SCI from the VA-Boston Chronic SCI cohort who completed a health questionnaire and underwent spirometry at study entry. Baseline data was linked to 1996–2003 hospitalization records from the VA National Patient Care Database. Not applicable. Cardiopulmonary hospital admissions, the predictors of which were assessed by Multivariate Cox regression. Of 1,478 admissions observed, 143 were due to cardiopulmonary (77 circulatory and 66 respiratory) illnesses. Independent predictors were greater age (3% increase /year), hypertension, and if in the lowest BMI quintile (<22.4 kg/m2). A greater %-predicted FEV1 was associated with reduced risk. SCI level and completeness of injury was not statistically significant after adjusting for these risk factors. Cardiopulmonary hospitalization risk in persons with chronic SCI is related to greater age and medical factors that, if recognized, may result in strategies for reducing future hospitalizations.
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