Development of a mobile low-field MRI scanner.
Development of a mobile low-field MRI scanner.
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DOI：
10.1038/s41598-022-09760-2
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发表时间：
2022-04-05
影响因子：
4.6
通讯作者：
Huentelman M
中科院分区：
文献类型：
--
作者：
Deoni SCL;Medeiros P;Deoni AT;Burton P;Beauchemin J;D'Sa V;Boskamp E;By S;McNulty C;Mileski W;Welch BE;Huentelman M
磁共振成像(MRI)可以对大脑和中枢神经系统的解剖和组织进行重要的可视化。然而，与脑电(EEG)或功能性近红外光谱分析不同，MRI仍然是一种以医院或中心为基础的方式。然而，低磁场强度的磁共振成像系统提供了超越这些传统医院和成像中心边界的潜力。在这里，我们描述了一种改装的货车的开发，它结合了一个可拆卸的低场永磁体磁共振系统，并展示了它的概念验证。使用体模扫描和活体T2加权神经成像数据，与实验室环境中类似的静态系统相比，我们显示在移动系统中获取的数据在几何失真、信噪比或组织分割结果方面没有显著差异。这些令人鼓舞的结果首次显示，核磁共振可以在参与者的家中、社区中心、学校等进行。这种移动方法打破了传统的访问障碍，可以对行动不便、住在距离成像中心很远的地方或无法前往成像中心或医院的患者和参与者进行成像。
Magnetic resonance imaging (MRI) allows important visualization of the brain and central nervous system anatomy and organization. However, unlike electroencephalography (EEG) or functional near infrared spectroscopy, which can be brought to a patient or study participant, MRI remains a hospital or center-based modality. Low magnetic field strength MRI systems, however, offer the potential to extend beyond these traditional hospital and imaging center boundaries. Here we describe the development of a modified cargo van that incorporates a removable low-field permanent magnet MRI system and demonstrate its proof-of-concept. Using phantom scans and in vivo T2-weighted neuroimaging data, we show no significant differences with respect to geometric distortion, signal-to-noise ratio, or tissue segmentation outcomes in data acquired in the mobile system compared to a similar static system in a laboratory setting. These encouraging results show, for the first time, MRI that can be performed at a participant’s home, community center, school, etc. Breaking traditional barriers of access, this mobile approach may enable imaging of patients and participants who have mobility challenges, live long distances from imaging centers, or are otherwise unable to travel to an imaging center or hospital.
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影响因子：
5
作者：
Fry A;Littlejohns TJ;Sudlow C;Doherty N;Adamska L;Sprosen T;Collins R;Allen NE
通讯作者：
Allen NE
影响因子：
2.9
作者：
Abiodun, Sade J.
通讯作者：
Abiodun, Sade J.
影响因子：
4.7
作者：
Casey BJ;Cannonier T;Conley MI;Cohen AO;Barch DM;Heitzeg MM;Soules ME;Teslovich T;Dellarco DV;Garavan H;Orr CA;Wager TD;Banich MT;Speer NK;Sutherland MT;Riedel MC;Dick AS;Bjork JM;Thomas KM;Chaarani B;Mejia MH;Hagler DJ Jr;Daniela Cornejo M;Sicat CS;Harms MP;Dosenbach NUF;Rosenberg M;Earl E;Bartsch H;Watts R;Polimeni JR;Kuperman JM;Fair DA;Dale AM;ABCD Imaging Acquisition Workgroup
通讯作者：
ABCD Imaging Acquisition Workgroup
影响因子：
5.7
作者：
Avants BB;Tustison NJ;Song G;Cook PA;Klein A;Gee JC
通讯作者：
Gee JC
影响因子：
5.7
作者：
Deoni, Sean C. L.;Bruchhage, Muriel M. K.;Williams, Steven C. R.
通讯作者：
Williams, Steven C. R.