Gender differences in colorectal cancer: implications for age at initiation of screening.
Gender differences in colorectal cancer: implications for age at initiation of screening.
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DOI：
10.1038/sj.bjc.6603628
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发表时间：
2007-03-12
影响因子：
8.8
通讯作者：
Haug, U.
中科院分区：
文献类型：
--
作者：
Brenner, H.;Hoffmeister, M.;Arndt, V.;Haug, U.
各国之间开始筛查结直肠癌（CRC）的年龄存在一定差异，但尽管CRC的流行病学存在重要的性别差异，但各国通常建议女性和男性的开始年龄相同。我们已经探讨了这些差异是否以及在多大程度上与开始CRC筛查时的年龄相关。使用来自美国的基于人群的癌症登记数据和来自不同国家的国家死亡率统计数据，我们研究了50岁，55岁和60岁男性中CRC的累积10年发病率和死亡率，发现女性主要在4至8岁时达到同等水平。性别差异在不同人群和不同时间都非常稳定。这些模式表明，性别差异的年龄在启动可能是值得的，以更有效地利用CRC筛查资源。
There is some variation regarding age at initiation of screening for colorectal cancer (CRC) between countries, but the same age of initiation is generally recommended for women and men within countries, despite important gender differences in the epidemiology of CRC. We have explored whether, and to what extent, these differences would be relevant regarding age at initiation of CRC screening. Using population-based cancer registry data from the US and national mortality statistics from different countries, we looked at cumulative 10-year incidence and mortality of CRC reached among men at ages 50, 55, and 60, and found that women mainly reached equivalent levels when 4 to 8 years older. The gender differences were remarkably constant across populations and over time. These patterns suggest that gender differentiation of age at initiation may be worthwhile to utilise CRC-screening resources more efficiently.
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影响因子：
254.7
作者：
Parkin, DM;Bray, F;Pisani, P
通讯作者：
Pisani, P
影响因子：
9.8
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de Garmo, P
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