Genetic associations with intimate partner violence in a sample of hazardous drinking men in batterer intervention programs.
Genetic associations with intimate partner violence in a sample of hazardous drinking men in batterer intervention programs.
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DOI：
10.1177/1077801214528587
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发表时间：
2014-04
影响因子：
2.2
通讯作者：
Temple JR
中科院分区：
文献类型：
--
作者：
Stuart GL;McGeary JE;Shorey RC;Knopik VS;Beaucage K;Temple JR
亲密伴侣暴力（IPV）的病因是多因素的。然而，IPV的病因学理论很少包括潜在的遗传因素。本研究的目的是检查是否累积遗传评分（CGS）包含MAOA和5-HTTLPR多态性与IPV犯罪后，占酒精问题，药物问题，年龄和关系的长度的影响。我们从罗得岛州的打人者干预项目中获得了97名男子的DNA。在整个样本中，CGS与对伴侣造成的身体和心理攻击和伤害显着相关，即使在控制了酒精问题，药物问题，年龄和关系长度的影响之后。样本中的两名男性可能患有克兰费尔特综合征，排除这两个人进行了重复分析，得出了相似的结果。遗传学研究结果的影响IPV的病因和治疗的男性之间的面糊干预计划进行了简要讨论。
The etiology of intimate partner violence (IPV) is multifactorial. However, etiological theories of IPV have rarely included potential genetic factors. The purpose of the present study was to examine whether a cumulative genetic score (CGS) containing the MAOA and 5-HTTLPR polymorphisms was associated with IPV perpetration after accounting for the effects of alcohol problems, drug problems, age, and length of relationship. We obtained DNA from 97 men in batterer intervention programs in the state of Rhode Island. In the full sample, the CGS was significantly associated with physical and psychological aggression and injuries caused to one's partner, even after controlling for the effects of alcohol problems, drug problems, age, and length of relationship. Two of the men in the sample likely had Klinefelter's syndrome and analyses were repeated excluding these two individuals, leading to similar results. The implications of the genetics findings for the etiology and treatment of IPV among men in batter intervention programs are briefly discussed.
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影响因子：
10.6
作者：
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通讯作者：
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