Label-free photoacoustic imaging of human palmar vessels: a structural morphological analysis.

Label-free photoacoustic imaging of human palmar vessels: a structural morphological analysis.
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DOI:
10.1038/s41598-018-19161-z
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发表时间:
2018-01-15
期刊:
影响因子:
4.6
通讯作者:
Toi M
Toi M
中科院分区:
综合性期刊3区
文献类型:
--
作者:
Matsumoto Y;Asao Y;Yoshikawa A;Sekiguchi H;Takada M;Furu M;Saito S;Kataoka M;Abe H;Yagi T;Togashi K;Toi M

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我们使用带有半球形探测器阵列的光声断层扫描 (PAT) 仪器分析了手掌的血管形态。无创地测定血管的三维(3D)形态。总共招募了 12 名女性和 11 名男性作为健康志愿者。他们的年龄分布几乎均匀,从 22 岁到 59 岁不等。在所有情况下,在皮肤下方观察到许多血管网络,并在解剖学上确定为静脉。为了分析主要动脉,从图像中移除了包含皮下静脉网络的层。分析的重点是掌指总动脉和固有动脉。我们使用这些动脉的曲率作为参数来分析它们的形态。将受试者作为一个整体进行比较时,性别之间的曲率没有显着差异。血管曲率随着年龄的增长而增加。 3D 数值分析结果与二维 (2D) 投影图像的主观评价之间具有良好的一致性。 PAT 系统可以实现手掌血管 3D 特征的可视化以及动脉迂曲度的无创分析。
We analysed the vascular morphology of the palm using a photoacoustic tomography (PAT) instrument with a hemispherical detector array. The three-dimensional (3D) morphology of blood vessels was determined noninvasively. Overall, 12 females and 11 males were recruited as healthy volunteers. Their ages were distributed almost evenly from 22 to 59 years. In all cases, many vascular networks were observed just beneath the skin and were determined to be veins anatomically. To analyse the major arteries, the layer containing the subcutaneous venous network was removed from the image. The analysis focused on the common and proper palmar digital arteries. We used the curvature of these arteries as a parameter to analyse their morphologies. There was no significant difference in the curvature between genders when comparing the subjects as a whole. The blood vessel curvature increased with age. Good agreement was found between the 3D numerical analysis results and the subjective evaluation of the two-dimensional (2D) projection image. The PAT system enabled visualization of the 3D features of blood vessels in the palm and noninvasive analysis of arterial tortuousness.
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