Quantitative effects of inclusion of fat on muscle diffusion tensor MRI measurements.
Quantitative effects of inclusion of fat on muscle diffusion tensor MRI measurements.
复制标题
DOI：
10.1002/jmri.24045
复制
发表时间：
2013-11
影响因子：
4.4
通讯作者：
Park, Jane H.
中科院分区：
文献类型：
--
作者：
Williams, Sarah E.;Heemskerk, Anneriet M.;Welch, E. Brian;Li, Ke;Damon, Bruce M.;Park, Jane H.
关键词：
To determine the minimum water percentage in a muscle region of interest that would allow diffusion tensor (DT-) MRI data to reflect the diffusion properties of pure muscle accurately. Proton density-weighted images with and without fat saturation were obtained at the mid-thigh in four subjects. Co-registered DT-MR images were used to calculate the diffusion tensor’s eigenvalues and fractional anisotropy. The eigenvalues transitioned monotonically as a function of water signal percentage from values near to those expected for pure fat to those for pure muscle. Also, the fractional anisotropy transitioned monotonically from 0.50 (fat) to 0.20 (muscle). For water signal percentages >55%, none of the diffusion indices differed significantly from those for regions of >90% muscle. Accounting for the T1 and T2 values of muscle and fat and the pulse sequence properties, it is concluded that, as a conservative estimate, regions must contain at least 76% muscle tissue to reflect the diffusion properties of pure muscle accurately.
登录
查看更多内容
影响因子：
3.3
作者：
Hernando, Diego;Liang, Zhi-Pei;Kellman, Peter
通讯作者：
Kellman, Peter
影响因子：
3.3
作者：
Damon, Bruce M.
通讯作者：
Damon, Bruce M.
影响因子：
4.4
作者：
Zaraiskaya, Tatiana;Kumbhare, Dinesh;Noseworthy, Michael D.
通讯作者：
Noseworthy, Michael D.
影响因子：
4.4
作者：
Qi, Jing;Olsen, Nancy J.;Park, Jane H.
通讯作者：
Park, Jane H.
影响因子：
3.3
作者：
Elder, Christopher P.;Cook, Ryan N.;Chance, Marti A.;Copenhaver, Elizabeth A.;Damon, Bruce M.
通讯作者：
Damon, Bruce M.